The spirodioxynaphthalenes of the preussomerin family, including 3 and 4, have been shown to exhibit broad range of biological activities.12 In our assays, ymf 1029C (4) showed relatively stronger cytotoxicity to NCI-H187 cells than other cell-lines. METHODS General experimental procedures ...
Chitosan is known as a semicrystalline polymer material with various types of crystal structures (polymorphism). It is a biodegradable, biocompatible, and renewable polymer material with antioxidant properties. Moreover, chitosan is non-toxic for humans and bioactive against selected microorganisms and vir...
The Materials Genome Initiative (MGI) advanced a new paradigm for materials discovery and design, namely that the pace of new materials deployment could be accelerated through complementary efforts in theory, computation, and experiment. Along with numer
KRAS is one of the most highly mutated oncoproteins, which is overexpressed in various human cancers and implicated in poor survival. The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecul
Zone C is buried deeper in the β subunit, further away from the interfacial surface. The connection between zones A and B (bridge) also projects towards the interfacial surface and can successfully allocate bridges of different sizes. Zones A and C are not so neatly divided and the ...
The hydrophobic surface exposure was measured by an 8-anilino-1-naphthalene sulfonic acid (ANS)-binding assay. Incubation of OTUB1 with ANS at 37 °C showed an increase in fluorescence intensity with time (Fig. 2D). The concentration-dependent ANS binding was observed in the case of OTUB1,...
By "para-oriented" is meant that the chain extending bonds from aromatic groups are either coaxial or parallel and oppositely directed, for example, substituted or unsubstituted aromatic groups including 1,4-phenylene, 4,4'-biphenylene, 2,6-naphthalene, and 1,5-naphthalene. Substituents on the ...
The aromatic sulfonamide compounds are selected from among the monosulfonamide derivatives of benzene, whether or not halogenated, of nitrobenzene, o-, m- or p-toluene, xylene, substituted or unsubstituted naph
The present invention relates to a process for the modification of the physical properties (viscosity, melting point, etc.), of colloidal substances and more specially to a process for the modification of the physical properties of organic isocolloids. By "isocolloids" 'or "isocolloidal substances...
4. The preparation method according to Claim 1, characterized in that the aromatic dicarboxylic acid is terephthalic acid, isophthalic acid, 2-methylterephthalic acid, 2,5-dichloroterephthalic acid, 2,6-naphthalenedicarboxylic acid, 1,4-naphthalenedicarboxylic acid, 4,4'-biphenyldicarboxylic acid or ...