the nature of which determine the MERCs function. Matrix, mitochondrial matrix; IMM, inner mitochondrial membrane; MIS, mitochondrial intermembrane space; OMM, outer mitochondrial membrane; MCU, mitochondrial calcium uniporter; VDAC, voltage-dependent ...
More precisely, the occurrence of inner membrane mitoptosis (IMM) was observed, where cristae and internal matrix of the mitochondria were lost while the external mitochondrial envelope remained unaltered. These structures were also observed in some cells of P-A PBS-treated MCTS, but to a ...
In virtually all multicellular eukaryotes, mitochondria are transmitted exclusively through one parent, usually the mother. In this short review, we discus... SJ Perlman,CN Hodson,PT Hamilton,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 0发...
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The microphthalmia/transcription factor E (MiTF/TFE) transcription factors are responsible for the regulation of various key processes for the maintenance
Mitochondria are the powerhouse of all living cells; they have a key role in several pathways such as apoptosis, Ca2+homeostasis, ROS signaling and mitophagy. They are also involved in carcinogenesis, cancer progression and metastasis, playing a role in altered energy metabolism of cancer cells. ...
Myricetin was also reported to suppress breast cancer metastasis through down-regulating the activity of the metalloproteinase matrix (MMP)-2/9 [137]. Another study by Rajendran et al. [138] reported that plant-based myricetin exhibited cytotoxic potential by inducing cell cycle arrest and ROS-...
which are synthesized by ribosomes in precursor forms. The incorporation of these precursors into specific mitochondria subcompartments such as the outer mitochondrial membrane (OMM), the intermembrane space (IMS), the inner mitochondrial membrane (IMM) and the mitochondrial matrix requires specific and...
[112]. Yan Runmin and colleagues developed a complex particle composed of magnetic paclitaxel-iron tetroxide-drug-loaded liposomes that can be directed to the intercellular matrix of brain tissue and penetrate cells through the BBB by means of magnetic field guidance in vitro. This novel strategy ...
morphological structure through transmission electron microscopy analysis, with swollen mitochondria, shortened or fragmented cristae, reduced granules in the matrix, significant expansion of the rough endoplasmic reticulum, widened intermembrane space of the vesicular structure, and visible autophagy in the ...