blood plasma,plasma,plasm- the colorless watery fluid of the blood and lymph that contains no cells, but in which the blood cells (erythrocytes, leukocytes, and thrombocytes) are suspended protein- any of a large group of nitrogenous organic compounds that are essential constituents of living ...
DEFINING THE PLASMA PROTEOME HISTORY OF SYSTEMATIC EXPLORATION THE KNOWN PLASMA PROTEOME DYNAMIC RANGE OF PROTEINS IN PLASMA PLASMA PROTEIN THERAPEUTICS PLASMA DIAGNOSTICS TRANSLATING THE PLASMA PROTEOME INTO USEFUL DIAGNOSTIC RESULTS CONCLUSIONS REFERENCESShow full outline Cited by (3803) Figures (6) Table...
We then review emerging opportunities provided by the protein corona to address major issues in healthcare and environmental sciences. This Review details how mechanistic insights into nanoparticle protein corona formation can broadly address unmet clinical and environmental needs, as well as enhance the ...
Corrigendum to: “Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study” [EBioMedicine 3 (216) 135–140] EBioMedicine, Volume 7, May 2016, Pages 287-288 Magnus Gisslén, Richard W. Price, Ulf Andreasson, Niklas...
Fasting plasma level of GLP1 was determined by Mouse Glucagon Like Peptide 1 (GLP1) ELISA Kit (Bioss) according to the manufacturer’s instructions. Briefly, plasma was obtained from 5 LFD and 5 HFD mice, protein levels were quantified, and analyzed according assay sample preparation guidelines...
A major benefit is the possibility of uncovering cell context-dependent, low-affinity, and stimulus-dependent transient interactions in minute-scale temporal resolution37. While proximity labeling may be less efficient in identifying low molecular weight protein interactors compared to conventional affinity-...
Joanna Kowal and his team showed several classical exosomes by proteomic analysis, and proteins such as major histocompatibility complexes (MHC), flotillin, and 70 kD heat shock protein were found in almost all EVs. They finally identified proteins that are specifically enriched in small EVs and ...
Insulin receptor (IR) controls growth and metabolism. Insulin-like growth factor 2 (IGF2) has different binding properties on two IR isoforms, mimicking insulin’s function. However, the molecular mechanism underlying IGF2-induced IR activation remains u
While observational studies and small pilot trials suggest that vitamin D, omega-3 and exercise may slow biological aging, larger clinical trials testing these treatments individually or in combination are lacking. Here, we report the results of a post hoc analysis among 777 participants of the DO...
Cetuximab therapy is the major treatment for colorectal cancer (CRC), but drug resistance limits its effectiveness. Here, we perform longitudinal and deep proteomic profiling of 641 plasma samples originated from 147 CRC patients (CRCs) undergoing cetuximab therapy with multi-course treatment, and 90...