However, other pathological brain processes are thought to be key disease mediators of Aβ plaque and NFT pathology. How these additional pathologies evolve over the course of the disease is currently unknown. Here we show that proteomic measurements in autosomal dominant AD cerebrospinal fluid (CSF...
The CP is the location of the blood-cerebrospinal fluid barrier (BCSFB), one of the barriers within the brain that prevents the entry of infectious agents to the central nervous system15,16,17,18. This study describes the gross, histopathological, IHC, and transmission electron microscopy (TEM...
Location of the plaques did not appear to affect its composition, that is, all the Aβ isoforms were present in plaques located in the cortex, hippocampus, or corpus callosum. It appeared that Aβ40 and Aβ42 were mainly present in the center of the plaques, whereas Aβ43 was present ...
In this analysis, the brain and skull considered to be solid material also the cerebrospinal fluid (CSF) to be fluid. The relationship between the skull and brain and CSF was determined by attention to complex geometry of the brain and skull. Solids analysis is performed by Ansys software and...
Moreover, NMOSD lesions are named “bright spotty lesions” when the T2 intensity is equal to or stronger than that of the surrounding cerebrospinal fluid (CSF) without flow void effects [5]. These T2 findings suggesting SCI or NMOSD surely help in the diagnosis; however, only a few studies...
Infection of the central nervous system by SARS-CoV-2 could be achieved by several routes: (i) the hematogenous route followed by a breakdown of the blood–brain barrier (BBB); (ii) through the blood-cerebrospinal fluid barrier (BCSFB); (iii) following retrograde axonal transport of SARS-Co...
Biological reactions to cerebrospinal fluid shunt devices: a review of the cellular pathology. Del Bigio MR. Biological reactions to cerebrospinal fluid shunt devices: a review of the cellular pathology. Neurosurgery 1998;42: 319-26... BMR Del - 《Neurosurgery》 被引量: 203发表: 1998年 Del Bi...
A biopsy can be obtained in several ways depending on the tumor location and surgical treatment plan, for example through endoscopy or needle biopsy [40]. If the sample obtained is too small, this can lead to misdiagnosis. In excisional biopsy, an entire area of abnormal cells is removed, ...
Tilted and rotated appearances are hallmarks of the myopic optic disc. As the eyeball grows axially, the posterior pole elongates not only globally but in a localized manner as well. In this process, the optic disc is pulled towards the deepest point of
Location of sections is indicated by their bregma positions, and the positions of the zoomed areas are as indicated. Neurons co-labeling with oxytocin (red) and CTB (green) are indicated by arrows. CTB was injected into the central amygdala of adult female mice, which were sacrificed 7 days...