Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibrob- lasts via activation of the Hedgehog signaling pathway. ... WT Liu,YY Jing,L Gao,... - 《Cell Death & Differentiation》 被引量: 0发表: 2019年 Gene Expression Profiles During Hepatic Stellate Cell Activation...
The aim of this study was to investigate the relationship between the eventual synthesis of PRL and PRLr isoforms with the inflammatory response in monocytes. We used THP-1 and monocytes isolated from healthy subjects stimulated with lipopolysaccharide (LPS). Western blot, real time PCR and immunocy...
Physiologically, lipopolysaccharide (LPS) is present in the bloodstream and can be bound to several proteins for its transport (i.e.) LPS binding protein (LBP) and plasma lipoproteins). LPS receptors CD14 and TLR-4 are constitutively expressed in the Central Nervous System (CNS). To our knowle...
Synthesis of lipopolysaccharide O-antigens by ABC transporter-dependent pathways. Carbohydr. Res. 356, 12–24 (2012). Article CAS Google Scholar Clarke, B. R., Cuthbertson, L. & Whitfield, C. Nonreducing terminal modifications determine the chain length of polymannose O antigens of ...
(PKB)/Akt kinase pathway [136]. IL-1, IL-2, IL-4, IL-5, IL-6, IL-12, IFN-γ, TNF-α, IL-10, and lipopolysaccharide are other proinflammatory cytokines that are linked to increased FoxO1 activity brought on by impaired insulin metabolism. It also influences how macrophages are ...
Kinase activities of RIPK1 and RIPK3 can direct IFN-β synthesis induced by lipopolysaccharide J. Immunol., 198 (2017), pp. 4435-4447, 10.4049/jimmunol.1601717 View in ScopusGoogle Scholar [18] H. Kato, O. Takeuchi, S. Sato, M. Yoneyama, M. Yamamoto, K. Matsui, S. Uematsu, A. ...
Kynurenine pathway metabolites and suicidality. Neuropharmacology. 2017;112:324–30. Article CAS PubMed Google Scholar Walker AK, Wing EE, Banks WA, Dantzer R. Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice. Mol ...
and gene therapy agents. Additionally, EV drug delivery have the advantage of being able to cross the blood‒brain barrier [125]. EVs can be classified based on their biogenesis or release pathway, including exosomes, microvesicles/microparticles, apoptotic bodies/blebs, large oncosomes, and other...
thereby forming pyroptosis. In addition, in the non-classical pathway, caspase-4/5/11 needs to directly recognize the lipopolysaccharide in the cytoplasm through the caspase activation and recruitment domain (CARD) domain25. In GSDMD-dependent pyroptotic pathway, there are mainly caused by stimulatio...
LPS Lipopolysaccharide EGF Epidermal growth factor Fuc Fucose Rha Rhamnose Ara Arabinose Gal Galactose Glc Glucose Xyl Xylose Man Mannose Rib Ribose GalA Galacturonic acid GlcA Glucuronic acid TG Thermogravimetric DTG Derivative thermogravimetry FRAP Ferric-Reducing Antioxidant Power References Wang, L.; Wu...