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The concentrations of the proteins were calculated by UV absorbance, using an extinction coefficient at 280 nm; this parameter was estimated from the number of tyrosines and tryptophans in each of these proteins [44]. In the remainder of the paper, PADI4 protein concentrations are expressed as ...
In addition to the D614G and N501Y mutation in RBD, variants B.1.351 and P.1 have acquired the E484K/T mutation in the RBD, respectively [41]. Variants with the K484 mutation have been reported to improve the affinity of RBD for ACE2 but only 1.4-fold [28]. They have also been ...