Liver eQTL studies using microarray expression quantification have been among the largest performed (after blood)15, and a recent liver eQTL meta-analysis16inn = 1183 individuals described evidence of sex-biased effects and colocalization for loci related to blood metabolite and lipid levels. The...
Biochemical complexes of lipids and soluble apolipoproteins that transport lipids in lymph fluid and blood to tissues throughout the body. The largest and least dense lipoproteins, chylomicrons, are assembled in the small intestine. Very low-density lipoproteins (VLDLs) and the smallest and most de...
echinocandins did not kill the ICG as effectively as planktonic cells (Fig.1a). Next, we treated ICG and planktonic cells with a wide range of micafungin concentrations (2X-256X MIC) and observed that the survival of ICG was 100–1000-fold higher than that of planktonic cells, especially at...
This is often the case for lung cancer patients due to the possible proximity of OARs like the heart, esophagus, trachea, large blood vessels and the spinal cord [4]. For early-stage NSCLC patients the outcomes achieved with proton therapy are similar to those achieved with stereotactic body ...
Health Risk Associated with Pesticide Contamination of Fish from the Densu River Basin in Ghana The Densu River Basin constitutes one of the largest agricultural areas in Ghana. The practice of using pesticides such as organochlorines, organophosphate... JR Fianko,A Donkor,ST Lowor,... - 《...
Parasitic kinetoplastids exhibit numerous adaptations to different energy resources. During its life cycle in the tsetse fly vector,T. bruceirelies on efficient catabolism of proline to succinate, acetate, and alanine as the main secreted end products, whereas in the blood of its vertebrate host, ...
Sugar dissolving in a cup of coffee is an example of diffusion. The sugar dissolves quickly in the hot drink, and the sugar molecules diffuse until they are uniformly distributed in the drink. The rate of diffusion depends on particle velocity, which in turn depends on the temperature, the ...
Currently, a systematic comparison of the neurotoxic effects of different particle types, shapes, sizes at different exposure concentrations and durations is lacking, but urgently needed to further elucidate the neurotoxic hazard and risk of exposure to micro- and nanoplastics. ...
1, the mouse xenograft model introduces a more complex environment including immune infiltrate, circulating blood, and many other cell types in the tumour microenvironment such as fibroblasts and cancer associated fibroblasts. Clinically, doses of DTX of 20 mg/m2 have been indicated to have radio...
High altitude hypoxia is a condition experienced by diverse populations worldwide. In addition, several jobs require working shifts where workers are exposed to repetitive cycles of hypobaric hypoxia and normobaric normoxia. Currently, few is known about