The microvillus-covered surface of epithelial cells found in enterocytes in the intestine. Warburg effect An aerobic process whereby cancer cells produce energy by a high rate of glycolysis followed by lactic acid fermentation in the cytosol rather than by oxidation of pyruvate in the mitochondria. ...
The ribosome has long been considered as a consistent molecular factory, with a rather passive role in the translation process. Recent findings have shifted this obsolete view, revealing a remarkably complex and multifaceted machinery whose role is to or
How did the large intestine get its name? What structure controls the passage of material from the small intestine to the large intestine? Are the kidneys a part of the digestive system? Is the stomach an exocrine gland? What are the folds in the small intestine called? Is the mouth an ...
1, S1). ACBD3 is structurally related to ACBD6, but instead of ankyrin-repeats the protein possesses a β-strand-rich GOLD domain in its C-terminal region, which can facilitate interactions with other proteins and may be used to stabilize peripheral membrane proteins at intracellular membranes...
At the same time, hepatic PXR, activated by LCA generated in the intestine, represses CYP7A1 and activates genes involved in bile acid metabolism (CYP3A). In addition, the studies cited in this review demonstrate that the metabolism of plasma lipoproteins is also significantly affected by these ...
(SC) system or SC family; the main storage site of vitamin A in the body is HSCs in the liver. In pathological conditions such as liver fibrosis, HSCs lose vitamin A, and synthesize a large amount of extracellular matrix (ECM) components including collagen, proteoglycan, glycosaminoglycan, ...
In contrast to digestible carbohydrates, non-digestible carbohydrates such as fiber and resistant starch are not enzymatically degraded in the small intestine. Rather, they travel to the large intestine where they undergo fermentation by resident microorganisms. Accordingly, dietary fiber is a good source...
67P is a comet located around 500 billion kilometers away from the Earth. Discovered in 1969 and named after its discoverers Churyumov-Gerasimenko, 6… Mathematics: On the Path to Wisdom 01 September 2015 | Asim Guvenalp | Issue 107 (September - October 2015) Throughout history, mathemat...
Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection. Nat. Med. 18, 1291–1296 (2012). CAS PubMed PubMed Central Google Scholar Ballester, M. et al. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG ...
et al. Small intestine early innate immunity response during intestinal colonization by Escherichia coli depends on its extra-intestinal virulence status. PLoS ONE 11, e0153034 (2016). Article PubMed PubMed Central CAS Google Scholar Russell, C. W. et al. Context-dependent requirements for FimH...