Reciprocally, it is well established that MM-derived factors stimulate osteoblast lineage cells to recruit and activate osteoclasts through receptor activator of nuclear factor kappa-Β ligand (RANKL) production. Osteoclasts degrade the bone matrix to release stored cytokines and growth factors (e.g.,...
Surprisingly, RNase activator G-1749 also did not increase the dimeric population (Fig.1e). These results suggest that while G-9807 acts as an allosteric RNase activator by stabilizing dimerization, G-1749 operates through a distinct mode, without altering the monomer-dimer equilibrium of IRE1. ...
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Another artificially engineered EV-based drug, exoSTING, which includes a cGAS‒STING pathway activator (cyclic dinucleotide) in the inner space and presents prostaglandin F2 receptor-negative regulator (PTGFRN) on the exosome surface, has entered phase I/II clinical trials in the treatment against...
MARPLE's autosurfing commonly led to the web page at https://en.wikipedia.org/wiki/JAK-STAT_signaling_pathway. The so-called JAK-STAT pathways, i.e. pathways involving the Janus kinase (JAK)-signal transducer and activator of transcription (STAT). Some of the same genes can also be ...
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Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes. Antimicrob. Agents Chemother. 2005, 49, 1745–1752. [Google Scholar] [CrossRef] [PubMed] [Green Version] Liu, Z.; Jian, Y.; Chen, Y.; Kistler, H.C....
In the autoclave treatment of powders, two approaches are used: the first is the heating of the oxide powder in the activator solution; the second, one activator is preliminarily applied on powder by the impregnation method, and powder is worked on in the medium of water vapor or fluid [...
AWS KMS Component 28.1. URI 格式 28.2. URI 选项 URI 选项 28.2.1. 路径名(1 参数): 28.2.2. 查询参数(8 参数): 28.3. Spring Boot Auto-Configuration 28.4. 使用 使用 28.4.1. MQ producer 评估的消息标头 28.4.2. KMS Producer 操作 28.5. 另请参阅 ...
28. AWS KMS 组件 AWS KMS 组件 28.1. URI 格式 28.2. URI 选项 URI 选项 28.2.1. 路径名(1 参数): 28.2.2. 查询参数(8 参数): 28.3. Spring Boot Auto-Configuration 28.4. 使用 使用 28.4.1. MQ producer 评估的消息标头 28.4.2. KMS Producer 操作 28.5. 另请参阅 ...