A wealth of research has emerged over the last five years showing the importance of extracellular vesicles (EVs) as mediators of intercellular communication. EVs range in size from 30 to 400 nm and according to the size have been classified as microvesicles, exosomes, and oncosomes. EVs are re...
K. et al. Reassessment of exosome composition. Cell 177, 428–445.e18 (2019). Article CAS PubMed PubMed Central Google Scholar Barman, B. et al. VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites. Dev. Cell 57, 974...
摘要 Human macrophages secrete extracellular vesicles (EVs) loaded with numerous immunoregulatory proteins. Vesicle-mediated protein secretion in macrophages is regulated by poorly characterized mechanisms; however, it is now known that inflammatory conditions significantly alter both the quantities and protein ...
Journal of Extracellular VesiclesK. W. Witwer, E. I. Buzas, L. T. Bemis, A. Bora, C. Lasser, J. Lotvall, E. N. N. Hoen, M. G. Piper, S. Sivaraman, J. Skog, C. Thery, M. H. Wauben, and F. Hochberg, Journal of Extracellular Vesicles, 2013, 2, 20360....
Extracellular vesicles (EVs) are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication, both in normal physiology and in pathological conditions. EVs can transfer functional proteins and genetic information to alter the phenotype and function of recipient cells, ...
Extracellular vesicles (EVs) are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication, both in normal physiology and in pathological conditions. EVs can transfer functional proteins and genetic information to alter the phenotype and function of recipient cells, ...
Stem cells (SCs) have been used therapeutically for decades, yet their applications are limited by factors such as the risk of immune rejection and potential tumorigenicity. Extracellular vesicles (EVs), a key paracrine component of stem cell potency, ov
As a particularly important mediator of intercellular communication, extracellular vesicles (EVs) have been proved to be extensively involved in various system diseases over the past two decades, including in renal diseases. As is well-known, renal fibrosis is the common pathological process of any ...
Extracellular vesicles (EVs, including exosomes) are implicated in many aspects of nervous system development and function, including regulation of synaptic communication, synaptic strength, and nerve regeneration. They mediate the trans... V Zappulli,KP Friis,Z Fitzpatrick,... - 《Journal of Clinica...
Secretion and Activation of Extracellular Vesicles from Various Cell Sources There is no definitive conclusion that different cells secrete EVs with different markers. However, few studies have found that some cells secreting EVs may carry the surface markers of those cells [13]. New studies also co...