In this chapter I explore the political and material context of a post-war Spain suffering the tragic loss of civil rights and material goods under the Franco dictatorship. I review the early days of penicillin,
doi:10.3810/pgm.1998.12.388Neil LovePostgraduate Medicine
So the discovery of penicillin paved the way for chemotherapy and other types of medical treatment – and topave the waymeans to make something possible.But surely, Alice, there are some bacteria that penicillin doesn't kill? Alice You...
However, the function of this structure remains unknown. Here we validate the micropore as an essential organelle for endocytosis of nutrients from the host cell cytosol and Golgi in the model apicomplexan Toxoplasma gondii. Detailed analyses demonstrated that Kelch13 is localized at the dense neck ...
In addition, the introduction of the 1,5-naphthyridine fragment was shown to increase the stability and to broad the spectrum of penicillins [34]. In the present study, 1,5-naph was reacted with three AgX salts (X = NO3−, CF3COO− and CF3SO3−), yielding new polynuclear ...
Introduction Lung cancer remains the primary cause of cancer-related deaths globally, with lung adenocarcinoma (LUAD) being its most dominant histological subtype1,2. Despite considerable progress in therapeutic approaches for LUAD, particularly with the introduction of immunotherapy, the prognosis remains...
are typically less active than the parent compound [98]. The carrier structure, typically lipophilic, must be biocompatible and capable of releasing the active compound as needed [99]. For instance, prodrug carriers are frequently utilized to enhance the bioavailability of oral penicillin drugs [100...
No other bacterial genus has been brought into context with so many different aspects of public interest as that of Pseudomonas (439): Pseudomonas aeruginosa is the germ responsible for most hospital infections (40a) being increasingly resistant against
The culture fluid contained 100 U/mL of penicillin/streptomycin. The cells were cultured in an incubator containing 5% CO2 at 37°C. 2.3. Cell Transfection si-circNBPF10, vector-circNBPF10, miR-224 mimics, miR-224 inhibitor, vector-PBX3, and corresponding control vectors were purchased from ...
Introduction The coronavirus disease 2019 (COVID-19) pandemic triggered by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has harmed billions of people globally and devastated the economy. It is thought to have emerged from a zoonotic source and spread quickly among humans through ...