人类蛋白质图谱(The Human Protein Atlas,HPA)是一个基于多组学技术的开放数据库,旨在全面解析人类蛋白质在正常组织、肿瘤、细胞系及亚细胞结构中的分布和功能。它整合了免疫组化、RNA测序、单细胞分析等多种实验方法,为科研人员提供可视化数据和定量表达信息,支持基础研究与...
THE HUMAN PROTEIN ATLAS,简称HPA,分为Cell,Tissue和Pathology三个版块,分别展示了蛋白在细胞、正常组织和癌变组织中的表达情况。 我以ITGB6为例,实操如何不做实验产数据。 打开proteinatlas.org/,在搜索框中输入ITGB6,点击search 点击图中绿色的Cell,进入该版块。 此版块分5个栏目,分别介绍了ITGB6的详细信息。 CE...
The Human Protein Atlas (HPA) project was initiated in 2003 with the goal to systematically map the expression of these proteins using antibody-based proteomics. The program is based primarily in Sweden with funding from the non-profit organization Knut and Alice Wallenberg Foundation (KAW). Antibo...
The Human Protein Atlas February 15, 2011 February 15, 2011 (Vol. 31, No. 4) URL: http://www.proteinatlas.org Rating: Strong Points: Beautiful images, different experimental methods represented Weak Points: None Summary: There are just some things that consistently make scientists happy. Among...
Human Protein Atlas 数据库,它致力于提供全部24,000种人类蛋白质的组织和细胞分布信息,并免费提供公众查询。创立这个数据库的瑞典 Knut & Alice Wallenberg基金会使用特制的抗体,用免疫组化的技术,检查每一种蛋白质在48种人类正常组织,20种肿瘤组织,47个细胞系和12种血液细胞内的分布和表达,其结果用至少576张免疫...
Tissue-, Cancer-andCell lineexpression, Antibody validation results in four different assays (IH=immunohistochemistry,IF=immunoflourescence,WB=Western blot,PA=Protein array), evidence scores and a filtration on Genes with antibodies only and Genes with knowledge-based annotated protein expression (IH,IF...
The Human Protein Atlas (HPA) program aims to map of all the human proteins in cells, tissues and organs using integration of various omics technologies, including proteomics, transcriptomics, antibody-based methods and AI-based systems biology. The current version (www.proteinatlas.org...
TheHumanProteinAtlas请注意甄别内容中的联系方式诱导购买等信息谨防诈骗 TheHumanProteinAtlas SEARCHi The search function can be used for free text search (type anything in the search field), or for more complex queries using 'Fields' (seeexamples). The free text search will scan for complete and...
cancers and cell lines. When the Human Protein Atlas was first launched, they were contacted by researchers wanting to obtain the antibodies used for the research. This is how Atlas Antibodies started, to commercialise the antibodies developed by the Human Protein Atlas project. We call these ant...
The Pathology Atlas是The Human Protein Atlas数据库(proteinatlas.org)中提供疾病相关研究数据的部分,它包含来自17种不同人类癌症的mRNA和蛋白质表达数据。 通过分析肿瘤组织中人类基因mRNA表达水平和近8000名癌症患者预后数据的相关性,得到18000多个具有显著性的结果(p <0.001),提示特定基因的表达与特定肿瘤的发生发展...