THP-1 is a human monocytic leukemia cell line. After treatment with phorbol esters, THP-1 cells differentiate into macrophage-like cells which mimic native monocyte-derived macrophages in several respects. Compared to other human myeloid cell lines, such as HL-60, U937, KG-1, or HEL cell ...
The human leukemia cell line, THP-1: A multifacetted model for the study of monocyte-macrophage differentiation THP-1 is a human monocytic leukemia cell line. After treatment with phorbol esters, THP-1 cells differentiate into macrophage-like cells which mimic native... J Auwerx - 《Experientia...
The human monocytic leukemia cell line THP-1, after stimulation with phorbol-12-myristate 13-acetate (PMA) for 24 h, shares many properties with human monocyte-derived macrophages16. Here we examined the ability of PMA-treated THP-1 macrophages (referred to as THP-1 macrophages) to promote ...
The human monocytic leukemia cell line THP-1 was obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA). The cells were maintained in RPMI 1640 medium containing 10% fetal bovine serum, 100 μg ml−1streptomycin and penicillin at 37 °C with 5% CO2. PYC was...
Similar to CAR-NK, CAR-M can be generated from different sources including peripheral blood, iPSCs and the human leukemia monocytic cell line THP-1 (Table4). PBMC derived M1 macrophages are characterized by their important production of proinflammatory factors such as IL-8, IL-6 and TNF-α ...
The FANTOM4 study identified transcriptional start sites active during proliferation arrest and differentiation of the human monocytic cell line THP-1. Systematic knockdown of 52 transcription factors provide support for their model in which a complex tr
18.acute myelo-monocytic leukemia急性粒-单核细胞白血病 相关短句/例句 human monocytic cell line人类单核细胞株 1.Expression of genes for inflammatory cytokines in human monocytic cell line THP-1 during exposure to isoflurane;目的研究异氟醚对人类单核细胞株(THP-1)细胞、白细胞介素-1β(IL-1β)、IL...
Leukemias are refractory hematological malignancies, characterized by marked intrinsic heterogeneity which poses significant obstacles to effective treatment. However, traditional bulk sequencing techniques have not been able to effectively unravel the h
Cell culture The human acute monocytic leukemia cell line (THP-1) and 293 T cells were obtained from Shanghai Institute of Cell Biology (Shanghai, China). The cells were incubated in RPMI 1640 medium supplemented with 1% antibiotic mixture and 10% fetal bovine serum under a 5% CO2 atmosph...
Additionally, the human monocytic cell lines THP-1 as well as BLaER1 cells, which can be transdifferentiated into a monocyte-like phenotype30, also displayed significant enrichment of LUCAT1 in a time-dependent manner when stimulated with LPS (Supplementary Fig 1c, d). RT-qPCR measures levels...