Target-controlled infusion (TCI) - a concept with a future: state-of-the-art, treatment recomm- endations and a look into the future[J].Anaesthesist, 2008, 57(3): 223-30.Schraag S, Kreuer S, Bruhn J, et al. Tar
Varveris DA, Morton NS (2002) Target controlled infusion of propofol for induc- tion and maintenance of anaesthesia using the paedfusor: an open pilot study. Paediatr Anaesth 12:589-593Varveris DA, Morton NS. Target controlled infusion of propofol for induction and maintenance of anaesthesia ...
Objective To study the effect of remifentanil given by target-controlled infusion(TCI) on the haemodynamic response to emergence from anesthesia and tracheal extubation.Methods Sixty ASA Ⅰ-Ⅱ female patients undergoing gynecological surgery were randomly assigned into two groups with 30 cases each: gro...
Clinical trials with pan-CDK inhibitors, such as flavopiridol, have demonstrated low levels of clinical activity and drug target selectivity. The reasons for their failure in the clinic include the absence of clear biomarkers for response and the lack of a clear therapeutic window. The selective CD...
G. The history of Toll-like receptors — redefining innate immunity. Nat. Rev. Immunol. 13, 453–460 (2013). Article PubMed CAS Google Scholar Takeuchi, O. & Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805–820 (2010). Article CAS PubMed Google Scholar Cani,...
13. Recent focus has also been on the role of the interneuronal perineuronal nets (PNNs) in the stabilization of memory circuits through tightened control of inhibitory inputs to dedicated neuronal assemblies14. Here we explored whether an overarching process could integrate stimulus-dependent and ...
CONCLUSIONS: The use of continuous HTS might achieve target sodium levels earlier compared to intermittent HTS. There was increased incidence of hypernatremia and hyperchloremia in continuous HTS groups. CLINICAL IMPLICATIONS: Continuous infusion of HTS may achieve sodium goals quicker but may require...
Rapoport first described in the early 1970s that infusion of hypertonic substances such as arabinose, urea or mannitol causes endothelial cells to contract, thereby increasing vascular permeability, effectively resulting in transient opening of the BBB [89]. Since then, the technique has been widely...
Randomized trials and long-term registry data are required to define the natural history, patient selection, and optimal treatment strategies for MB. Funding Support and Author Disclosures Dr Sharma has received consultant fees from Abbott Vascular, Boston Scientific, and Cardiovascular Systems, Inc. ...
Propofol was administered using a target-controlled infusion (TCI) pump to obtain constant effect site concentration as estimated by Marsh model. Under general anesthesia, remifentanil (1.0 μg/kg) and succinylcholine (1.5 mg/kg) were administered for ease of endotracheal intubation. Starting...