Wnt/beta-catenin signaling in development and disease. Cell 127, 469–480 (2006). Article CAS PubMed Google Scholar Kwon, Y. et al. The Hippo signaling pathway interactome. Science 342, 737–740 (2013). Article ADS CAS PubMed PubMed Central Google Scholar Wilson, M.A. Searching for ...
substantial efforts have been made to understand the upstream signals that influence the activity of the Hippo pathway, as well as its physiological functions, such as cell proliferation and differentiation, organ growth, embryogenesis, and tissue...
Like p53, FOXP3 also interacts directly with theLATS2promoter to induceLATS2expression.92Interestingly, the levels of FOXP3 are positively regulated by MST,93representing an additional mechanism by which MST promotes LATS2 activity. Intriguingly, also within the Hippo pathway, YAP/TAZ and their can...
We further analyzed properties of GWAS+ cluster. This cluster is enriched in theHippo signaling pathway(KEGG:04390) (Bonferroni-correctedp-value = 1.56e−3),WNT Signaling Pathway(KEGG:04310) (Bonferroni-correctedp-value = 9.57e−3) andPathways in cancer(KEGG:05200) with genes s...
A series of unbiased Hippo pathway interactome studies have linked endosomal compartments to the Hippo pathway (Moya and Halder, 2014). It is possible that the Hippo pathway may regulate endocytic trafficking and, therefore, regulate EV biogenesis. Little is known about the signaling mechanisms involv...
Finally, to elucidate SKI's effects on Hippo signaling, the SKI and TAZ interactomes were captured in human cardiac fibroblasts using BioID2 and mass spectrometry. Potential interactors were investigated in vitro to reveal novel mechanisms of action for SKI. In vitro assays on elastic substrates ...
Discovering the Hippo pathway protein-protein interactome. Cell Res 2014;24:137-8.Moya IM, Halder G. Discovering the Hippo pathway protein-protein interactome. Cell Res 2014; 24:137-138.Moya, I. M. & Halder, G. Discovering the Hippo pathway protein-protein interactome. Cell Res. 24, 137-...
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The hippo pathway in heart development, regeneration, and diseases Circ. Res., 116 (2015), pp. 1431-1447 View in ScopusGoogle Scholar [141] A. Li, F. Ponten, C.G. dos Remedios The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart ...
The Hippo signaling pathway interactome. Science 2013; 342: 737–740. 118. Wang W, Xiao Z-D, Li X, Aziz KE, Gan B, Johnson RL et al. AMPK modulates Hippo pathway activity to regulate energy homeostasis. Nat Cell Biol 2015; 17: 490–499. 119. Mo J-S, Meng Z, Kim YC, Park HW...