This study reanalyzes Swedish cohort data to assess the stability under alternative assumptions and models of a previous estimate of the heritability of
In the last 30 years, twin studies have indicated a strong genetic contribution to Autism Spectrum Disorders (ASD). The heritability of ASD is estimated to be 50%, mostly captured by still unknown common variants. In approximately 10% of patients with ASD, especially those with intellectual ...
et al. The heritability of autism spectrum disorder. JAMA 318, 1182–1184 (2017). Article PubMed PubMed Central Google Scholar Grove, J. et al. Identification of common genetic risk variants for autism spectrum disorder. Nat. Genet. 51, 431–444 (2019). Article CAS PubMed PubMed ...
We also found that the heritability for the 4 cutoffs was similar. Conclusion We demonstrate an etiological similarity between ASDs and ALTs in the normal variation and, with results from previous studies, our data suggest that ASDs and ALTs are etiologically linked. Autism spectrum disorders (...
The heritability of autism spectrum disorder. JAMA. 2017;318(12):1182–1184. doi:10.1001/jama.2017.12141 19. Hallmayer J, Cleveland S, Torres A, et al. Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry. 2011;68(11):1095–1102. doi:...
Autism spectrum disorder(ASD)is one of the most prevalent groups of neurodevelopmental disorders.It is defined by defects in social and linguistic abilities,and limited interests as well as repetitive behavior,with a few exceptions.Based on the autism spectrum disorder concordances,monozygous twins have...
Heritability of autism spectrum disorder in a UK population-based twin sample. JAMA Psychiatry. 2015;72(5):415–23. Article PubMed PubMed Central Google Scholar McElhanon BO, McCracken C, Karpen S, Sharp WG. Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis. Pediatrics. ...
The Genetics of Autistic Disorders and its Clinical Relevance: A Review of the Literature Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the narrow and broad phenotype of AD. In this review on the genet... CM Freitag - 《Mol Psychiatry》 被引量: ...
♠Couldmultivitamin use in pregnancyprotect children from autism? Yet, the research was entitled: ♦The Heritabilityof Autism Spectrum Disorder ♣Mum’s bacterialinked to baby’s behavior ♠Antenatal nutritional supplementationand autism spectrum disorders in the Stockholm youth cohort: population ba...
IMPORTANCE: Autism spectrum disorder (ASD) aggregates in families, but the individual risk and to what extent this is caused by genetic factors or shared or nonshared environmental factors remains unresolved. OBJECTIVE: To provide estimates of familial aggregation and heritability of ASD. DESIGN, SETT...