Our findings demonstrate that gut microbiota mainly modulate the mutual transformation of microglial subtypes, which may lead to new insights into the pathogenesis of AD and MDD.Similar content being viewed by others The gut microbiome is associated with brain structure and function in schizophrenia ...
There is now growing evidence that disruptive changes in the gut microbiome are strongly associated with the development colorectal cancer. However, how the gut microbiome changes with time during tumorigenesis and whether these changes directly contribute to disease have not been determined. We ...
While secretory products, such as gut-derived metabolites may mediate gut-brain connection, there is also a direct connection via the vagus nerve [56]. The vagus nerve is the longest cranial nerve in the body and stretches from the large intestine to the brain. It is critical in involuntary ...
Our findings indicate that the gut microbiome structure is highly variable depending on region of sampling, but most interestingly, we identify unique enrichments of bacterial species and functional pathways that potentially modulate the susceptibility of konzo in prone regions of the Congo....
The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which contributes to a variety of physiological functions. The GM is highly dynamic, being sensitive to environmental stimuli, and its composition changes over the host’s entire lifespan. However, the basic question of...
While secretory products, such as gut-derived metabolites may mediate gut-brain connection, there is also a direct connection via the vagus nerve [56]. The vagus nerve is the longest cranial nerve in the body and stretches from the large intestine to the brain. It is critical in involuntary...
(also known as the brain-gut axis), is thought to be involved in many regular functions and systems within the healthy body, in addition to the pathogenesis of many diseases from neurological and degenerative conditions to autoimmune diseases. The gut-brain axis is now being investigated as a ...
Dietary fibre positively influences gut microbiome composition, enhancing the metabolism of dietary flavonoids to produce bioactive metabolites. These synergistic activities facilitate the beneficial effects of dietary flavonoids on cardiometabolic health parameters. The aims of this study were to investigate whe...
While the microbiome of a healthy individual is relatively stable, gut microbial dynamics can certainly be influenced by host lifestyle and dietary choices [26]. In this review, we comprehensively explore the ability of the host diet to modulate gut bacteria, with the hope that this knowledge ...
High-fat (HF) diets are thought to disrupt the profile of the gut microbiota in a manner that may contribute to the neuroinflammation and neurobehavioral changes observed in obesity. Accordingly, we hypothesize that by preventing HF-diet induced dysbiosi