These neurons are stimulated in response to sugar but not artificial sweeteners, and are activated by direct delivery of sugar to the gut. Using functional imaging we monitored activity of the gut–brain axis, and identified the vagal neurons activated by intestinal delivery of glucose. Next, we...
sweet taste: Trpm5−/− ;Tas1r2−/−Tas1r3−/− 通过对不同队列的小鼠摄入糖水后进行c-Fos染色发现,孤立束的尾核(cNST)上有明显的双侧标记,作者考虑直接从胃直接注入糖,发现也能激活cNST,说明这一部分神经会选择性的“吃糖”,并且独立于味觉传导通路。 胃-肠轴通过迷走神经将信息传递到大脑, 当...
Guided by gut sensory cues, humans and animals prefer nutritive sugars over non-caloric sweeteners, but how the gut steers such preferences remains unknown. In the intestine, neuropod cells synapse with vagal neurons to convey sugar stimuli to the brain within seconds. Here, we found that cholecy...
江南大学最新论文揭示调控糖偏好的秘密 | 近日,江南大学朱升龙、陈永泉,及中国科学院大连化学物理研究所梁鑫淼等人,在 Nature 子刊 Nature Microbiology 上发表了题为:Free fatty acid receptor 4 modulates dietary sugar preference via the gut microbiota 的研究论文。
Next is the braising process. The braising of Pingqiao Tofu is extremely particular. It is necessary to choose original chicken broth or meat broth as the base soup, enhanced with lard, scallions, ginger, carp brain, crab roe...
the mechanisms underpinning such effects are only beginning to be resolved. Microbiota–gut peptide interactions are poised to be of great significance in the regulation of gut–brain signaling. Given the emerging role of the gut–brain axis in a variety of brain disorders, such as anxiety and ...
With this observation, the gut microbiome became a part of the gut-liver axis and a target for treatment of numerous metabolic diseases affecting the liver, discussed in detail subsequently. Moreover, hepatosteatosis and NAFLD are common co-morbidities of inflammatory bowel disease (Chao et al., ...
The gut microbiota produces a host of bioactive metabolites that can alter the body’s homeostatic state allowing it to react to stressful conditions in a more adaptive manner (Westfall and Pasinetti, 2019). Generally classified as gut-brain-axis mechanisms, some of these adaptations include immun...
Cognitive, Affective, & Behavioral Neuroscience (2018) 18:1121–1144 https://doi.org/10.3758/s13415-018-0626-0 The brain-adipocyte-gut network: Linking obesity and depression subtypes Carla M. Patist1 & Nicolas J. C. Stapelberg 1,2 & Eugene F. Du Toit3 & John P. Headrick3 ...
Conversely, signals from the brain can influence the composition and function of the gut microbiota. This bidirectional communication across the gut microbiota–brain axis, involving multiple biochemical and cellular mediators, is recognized as a major brain–body network that integrates cues from the ...