ECONOMIC aspects of diseasesNOSOLOGYNon‐alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease. Global Burden of Disease (GBD) data from 1990 to 2019 reported a rise in prevalence (9–13%) in Australia, which also ranked third highest for NAFLD prevalence compa...
Published data from the World Health Organization and/or the Global Burden of Disease show that the burden of CLD is large and increasing, primarily owing to the increasing burden of nonalcoholic fatty liver disease and alcohol-related liver disease (ALD). Middle Eastern, Northern African, and ...
Liver disease is a major cause of illness and death worldwide. In China alone, liver diseases, primarily viral hepatitis (predominantly hepatitis B virus [HBV]), nonalcoholic fatty liver disease, and alcoholic liver disease, affect approximately 300 million people. The establishment of the Expanded...
Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384, 766–781 (2014). Article Google Scholar Heymsfield, S.B. & Wadden, T.A. Mechanisms, pathophysiology, ...
Furthermore, FOXA1 reduces lipid accumulation in human hepatocytes, and expression levels are downregulated in non-alcoholic fatty liver disease [57]. In alcoholic liver disease, FOXA1 and FOXA2 appear to act synergistically. Hepatocyte nuclear factor 4, alpha (HNF4α) is an important ...
Although DALYs from all other liver diseases have remained stable in the last decade, DALYs related to NAFLD/NASH are growing. National, regional, and global policies are needed to address the disability burden of NAFLD across the world.
The Global Burden of Disease Study 2013 and the WGO recommendations are additional clarion calls to address the highly prevalent epidemic of adult and childhood obesity and its attendant complications, specifically NAFLD. Increased awareness of the scope and impact is a much needed and welcomed first...
Thus, China plays an important role in the global burden of liver disease. Several types of liver diseases, including chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, alcoholic liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), and other liver diseases, ...
Increased circulating zonulin in children with biopsy-proven nonalcoholic fatty liver disease. World J Gastroenterol 2014; 20: 17107–17114. Article Google Scholar Dastych M, Dastych Jr M, Novotna H, Cihalova J . Lactulose/mannitol test and specificity, sensitivity, and area under curve of ...
Maternal overnutrition during sensitive periods of early development increases the risk for obesity and neuropsychiatric disorders later in life. However, it still remains unclear during which phases of early development the offspring is more vulnerable.