The involvement of TRIB1 in hepatic lipid metabolism has been validated through viral-mediated hepatic overexpression of the gene in mice; increasing levels of TRIB1 decreased plasma lipids in a dose-dependent manner. The TRPS1 encodes a transcription factor interacted with a dynein light chain ...
Diabetes, a major non-communicable disease, presents challenges for healthcare systems worldwide. Traditional regression models focus on mean effects, but factors can impact the entire distribution of responses over time. Linear mixed quantile regression
it is the first systematic review and meta-analysis on the LAP index and NALFD in the literature. Third, by including 96,101 individuals with and without NAFLD, a conclusive result with high precision and low bias may have been achieved for the general population...
To test this, we assessed the global impact of SMPDL3B on the cellular lipid repertoire by mass spectrometry-based lipidomics. RAW264.7 cells were incubated for 2 hr in serum-free medium and lipids from control (shCTRL) and SMPDL3B-depleted cells (shSMPDL3B) were extracted and analyzed ...
this pig population was transferred to the experimental test station at theCentre de Control Porcí(CCP) of theInstitut de Recerca i Tecnologia Agroalimentàries(IRTA). Serum lipids were measured in 45 and 190 days-old pigs by following the protocols reported by Gallardo et al. [5]. Data (...
et al. Effect of dietary sodium intake on blood lipids. Hypertension. 2004;43:393-398Google ScholarCrossref 11. Hokanson JE, Austin MA. Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level. J Cardiovasc Risk. 1996;3:...
Lipids in Health and Disease volume 23, Article number: 249 (2024) Cite this article 636 Accesses Metrics details Abstract Background Existing studies have presented limited and disparate findings on the nexus between immune cells, plasma metabolites, and metabolic dysfunction-associated steatotic liver...
Lipids: Summary of Meta-Analysis Results for Trials Evaluating Lifestyle Interventions for People With Prediabetes (KQ9) eFigure 4. Weight and BMI: Summary of Meta-Analysis Results for Trials Evaluating Lifestyle Interventions for People With Prediabetes (KQ9) eReferences 1. National diabetes ...
Asymmetric distribution of lipids across the two leaflets of biological membranes is a general feature of eukaryotic cells13. Scramblases, flippases, and floppases are the main types of membrane transporters that facilitate lipid translocation across the plasma membrane, thereby affecting intracellular ...
Ocular delivery of lipid nanoparticle (LNPs) packaged mRNA can enable efficient gene delivery and editing. We generated LNP variants through the inclusion of positively charged-amine-modified polyethylene glycol (PEG)-lipids (LNPa), negatively charged-ca