n.Abbr.T4 An iodine-containing hormone, C15H11I4NO4, produced by the thyroid gland, that increases the rate of cell metabolism and regulates growth. A synthetic form is used in the treatment of thyroid disorders. [thyr(o)-+ox(y)-+in(dole).] ...
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Unfortunately, therapeutic use of FGF-21 has been limited because of concerns for off-target effects (Kharitonenkov and Adams 2014) possibly due to the systemic administration of the hormone in pharmacologic doses, unlike the local, paracrine action within the adipose tissue depots. The discovery ...
The influence of human growth hormone (HGH) on the thyroxine (T4)-triiodothyronine (T3)-ratio in HGH deficient patientsPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology...
We simply aren’t meant to live for conversion alone to T3–the active thyroid hormone.Plus there are just many life situations that can cause that T4 to convertReverse T3, the inactive hormone. **You can read a lot more interesting information about T4-only in Chapter 1 of theupdated rev...
Download: Download full-size image Fig. 2. TRH secretion by the hypothalamus. Magnocellular neurons (MCN) of the paraventricular nucleus (PVN) produce peptides that are transported to the posterior part of the pituitary gland by axonal transport. Thyrotropin-releasing hormone (TRH) secreted by par...
Type 1 insulin-like growth factor receptor (IGF1R) is a receptor tyrosine kinase that regulates cell growth and proliferation, and can be activated by IGF1, IGF2, and insulin. Here, we report the cryo-EM structure of full-length IGF1R–IGF1 complex in th
Phares CK: The growth hormone-like factor from plerocercoids of the tapeworm Spirometra mansonoides is a multifunctional protein. In Effects On Host Hormones and Behavior, Parasites and Pathogens. Edited by Beckage NE. 1997:99–112. Liu LN, Cui J, Zhang X, Wei T, Jiang P, Wang ZQ: ...
coloniale, mainly involved in bio- logical process categories such as photosynthesis-antenna proteins, plant–pathogen interaction and plant hormone signal transduc- tion (Supplementary Table 6). Thus, it is reasonable to expect that these unique biological traits reflect adaptations of P. coloniale to...
In tumor MA-10 Leydig cells, treated with different concentrations of Roundup, the expression of aromatase and steroidogenic acute regulatory protein (StAR) also decreased [52]. GBHs and their adjuvants were able to induce proliferative effects in human hormone-dependent breast cancer cells, further...