As defined in the scopes of the journals Current Research in Biotechnology and Current Opinion in Biotechnology, major themes of biotechnology research include genetic and molecular engineering; tissue, cell, and pathway engineering; plant and animal biotechnology; food biotechnology; energy biotechnology;...
Aureolysin, a secreted metallopeptidase (MP) from the thermolysin family, functions as a major virulence factor in Staphylococcus aureus. No specific aureolysin inhibitors have yet been described, making this an important target for the development of novel antimicrobial drugs in times of rampant antib...
shown to scale with the four protein structures previously solved at the EuXFEL by using MHz repetition rates for comparison. Views from the membrane plane (top) and membrane normal (bottom) are shown for the PSI trimer, with major and minor axes denoted. Protein subunits are colored ...
Abscisic acid (ABA) and auxin signalling pathways played a major role in seed germination of wheat. Stress related proteins were also found with acetylation changes, some of which have been reported to be associated with seed germination and others are unknown in plants. Several enzymes that play...
The independent variables included the mRNA and protein levels of the biomolecules involved in TGF-β3 signaling, cell proliferation, and migration. The experiments above were repeated at least in triplicate. The level of significance was set at P≤ 0.05. RESULTS YOD1 Overexpression in HOKs ...
Transcriptome and metabolome analysis to reveal major genes of saikosaponin biosynthesis in Bupleurum chinense. BMC Genom. 2021;22(1):1–14. 26. Wang Y, Huang L, Du F, Wang J, Zhao X, Li Z, et al. Comparative transcrip- tome and metabolome profiling reveal molecular mechanisms underly-...
Cadmium affects several cellular processes including cell cycle progression, proliferation, differentiation, DNA replication, and apoptosis [133], which may play a major role in Cd genotoxicity [134]. This process is also true for other diseases caused by exposure to Cd such as lung, prostate, or...
Selection pressure governs the relative mutability and the conservedness of a protein across the protein family. Biomolecules (DNA, RNA and proteins) continuously evolve under the effect of evolutionary pressure that arises as a consequence of the host p
major adverse reactions in animals identified at a certain dose (toxic dose) within 24 h, a decreased dose (usually the mean value between toxic dose and last tolerated dose) were applied to a new group of mice. Animals (one or more) may have shown the onset of major adverse reactions...
Biomolecules 12, 205 (2022). Article CAS PubMed PubMed Central Google Scholar Download references Acknowledgements This work was funded by , the Guangxi Science and Technology Major Project to XJ Bei (AA22068092), the Joint Agricultural Basic Research Project of Yunnan province to SH Wang (...