The perichromosomal layer is indicated by arrows, and the prenucleolar bodies of telophase cells are indicated by arrowheads. (E) EGFP-R19 bound with interphase prenucleolar bodies (arrowheads), which formation was induced by hypotonic treatment. (F) EGFP-19 is not a component of the nuclear ...
Retention of CCAN proteins in a few discrete orders in the subphyla of Pucciniomycotina and Ustilogamycotina suggests the occurrence of multiple independent loss events of most CCAN subunits (Fig.1a). The kinetochore linker CENP-CMif2was the only conserved CCAN component across basidiomycetes. Ot...
The cell cycle is the sequence of events that take place to enable DNA replication and cell division. It can be divided into two phases: interphase and mitosis. Interphase is further divided into t...
1d). As the nuclear envelope reforms at the end of mitosis, we speculated that nuclear export of GEN1 must occur at telophase, and that LMB might specifically block the transport of GEN1 to the cytoplasm at this stage of the cell cycle. This was indeed shown to be the case because, in...
End of telophase II (number per nucleus) Cell Division: Cell division is a fundamental process by which cells reproduce and multiply. It involves the replication and distribution of genetic material, followed by the division of the cell into two daughter cells, ensuring growth...
CHROMATIN LICENSING (EARLY G1) One of the earliest events in the cell cycle is chromatin licensing, which is the process that allows various proteins and complexes to get access to chromatin. These include primarily DNA replication factors and chromatin modification proteins related to...
In telophase II, what is the c-value for one of the cells that is in this stage of meiosis (assuming no problematic (non-disjunction) events occur)? Consider a diploid cell that undergoes meiosis with 44 total chromoso...
Acetylation is one of the major post-translational protein modifications in the cell, with manifold effects on the protein level as well as on the metabolome level. The acetyl group, donated by the metabolite acetyl-coenzyme A, can be co- or post-translationally attached to either the α-amino...
of nucleolar morphology with great precision (Montgomery1898). In 1934, McClintock proposed that the “nucleolus is organized in the telophase through the activity of ... the nucleolar-organizing body” (McClintock1934). Since the nucleolar-organizing body corresponds to a specific region of ...
(Fig.6a), TPX2-AURKA (Supplementary Fig.5a) and TPX2-KIFC1 (Supplementary Fig.5b) depicted strong PLA signals from prophase (within the centrosomal asters) through metaphase to telophase (more at the spindle poles). This data indicated a colocalization of AURKA, KIFC1 and TPX2 during ...