becoming increasingly evident that maternal starvation during pregnancy can have permanent effects on a range of physiological processes in the offspring, scant information is available about the consequence of
Women are born with all of their oocytes. The oocyte proteome must be maintained with minimal damage throughout the woman’s reproductive life, and hence for decades. Here we report that oocyte and ovarian proteostasis involves extreme protein longevity. Mouse ovaries had more extremely long-lived...
In animals with heterogametic sex determination, accumulation of HI genes on the sex chromosomes would compromise fitness in both sexes, given X chromosome inactivation in females. We found that orthologues of S. cerevisiae HI genes are significantly under-represented on the X chromosomes of mammals...
Ascomycetes are named after the ascus, a sac-shaped structure that contains ascospores, the products of meiosis during the sexual reproductive process. Asci are formed when the female sex cell (ascogonium) is fertilized by the male gamete (antheridium). The diploid zygote nucleus undergoes meiosis...
Mostofthepropertiesweassociatewithlifearepropertiesofthecytoplasm.Muchofthemassofacellconsistsofthissemifluidsubstance,whichisboundedontheoutsidebytheplasmamembrane.Organellesaresuspendedwithinit,supportedbyt..ofthecytoskeleton.Dissolvedinluidarenutrients,ions,solubleproteins,andothermaterialsneededforcellfunctioning....
The silver-lipped pearl oyster, Pinctada maxima, is an important tropical aquaculture species extensively farmed for the highly sought "South Sea" pearls. Traditional breeding programs have been initiated for this species in order to select for improved
‘Causa latet, vis est notissima’ [The cause is hidden, the result is very evident], Ovidius, Metamorphoses, IV. 287. 1. Introduction Biomedical science's courses comprise studies on the reproductive systems in which gonads in all animals, including humans, are included. The male testes ...
In the presence of horizontal gene transfer (HGT), the concepts of lineage and genealogy in the microbial world become more ambiguous because chimeric genomes trace their ancestry from a myriad of sources, both living and extinct. We present the evolutio
T. brucei has a single flagellum that is present throughout the parasite and its life cycle. The flagellum has conserved and unique features. It emerges from a membrane invagination at the posterior end of the cell and remains attached to the cell body for most of its length. The flagellum...
Moreover, enrichment of stop codon sequences was only observed directly at the 5′ end of piRNAs at position 1–3 (Fig. 1a), suggesting that it is not driven by a general over-representation of stop codons in pachytene piRNA clusters. Similar enrichment was observed across the whole length...