Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we characterized mutational signatures using 84,729,690 somatic mutations from 4,645 whole-genome and 19,184 exome sequences that encompass most types of cancer...
TAAD encompass a spectrum of aortic pathology affecting the aortic root, the ascending aorta, the aortic arch and the descending thoracic aorta. Thoracic aortic aneurysms, a dilation of the proximal aorta, are known to progressively enlarge over time, ultimately leading to rupture and death if not...
experienced an increase in depressive symptoms, the autistic group showed the opposite effect over time. It must be noted, however, that children completed measures at different times to one another, making detailed understanding of the different trajectories more difficult to elicit here. In the wid...
As described for peripheral macrophages, the functions acquired by microglia during the process of activation can either promote or attenuate the inflammatory response, and though not yet fully defined, the repertoire of microglial phenotypes is likely to encompass the full spectrum ranging from the ...
meaning diluted. In this way, the term “gay” is used as a generic shorthand for all LGBTQ+ people, which potentially leads to “diversification of the term to the point of meaningless homogenization” (Bitterman2020, 100). That is, as the LGBTQ+ umbrella has expanded to encompass more...
partnered to deliver digital solutions that help simplify and automate business finance functions at enterprises. As a strategic partner, Wipro will offer its clients Trintech's portfolio of financial solutions, which encompass high-volume transaction matching, balance sheet and intercompany reconciliations,...
These staging systems are not optimal since they have been developed for all head and neck SCCs, which encompass tumours with very different aggressiveness. They also lack extensive validation, as they have been only validated in series of organ transplant recipients with cSCC [43]. In addition,...
Finally, if the Mix hypothesis is correct, activation will be normally distributed (the bias of the system) but shifted towards the most frequent item in the input (which might not be the center of the input) and encompass all studied items. This will result in an activation gradient that ...
Understanding and exploiting genetic diversity is a key factor for the productive and stable production of rice. Here, we utilize 73 high-quality genomes that encompass the subpopulation structure of Asian rice (Oryza sativa), plus the genomes of two wild relatives (O. rufipogonandO. punctata), ...