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The emerging field of lipidomics tries to define the crucial role of lipids in the cell; the research is aimed at mapping the entire lipid population in a biological system, describing the composition and biological function. The main progress that has spurred recent advances in lipid analysis wa...
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Establishment and maintenance of pregnancy depends on progesterone synthesized by luteal tissue in the ovary. Our objective was to identify the characteristics of lipid droplets (LDs) in ovarian steroidogenic cells. We hypothesized that LDs are a major f
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Finally, general therapeutic strategies for ferroptosis sensitization based on the manipulation of the lipidome in ferroptosis-resistant cancer cell lines are proposed. Keywords: ferroptosis; cancer cells; de novo lipogenesis; ketolysis; lipidomics; metabolic reprogramming; cancer treatment; therapeutic ...
The activity of the commensal microbiota significantly impacts human health and has been linked to the development of many diseases, including cancer. Gnotobiotic animal models have shown that the microbiota has many effects on host physiology, including
To elucidate the potential of Au@Pt in regulating glucose and lipid metabolism, we analyzed liver and feces under high-fat diet (HFD) conditions following Au@Pt administration through the integration of multi-omics analysis. We found that Au@Pt was effective in reducing blood glucose levels and...