Lipid MetabolismClinical Trials as TopicThe crucial role of lipids in cell, tissue and organ physiology is demonstrated by a large number of genetic studies and by many human diseases that involve the disruption of lipid metabolic enzymes and pathways. Examples of such diseases include cancer, ...
The emerging field of lipidomics 来自 Semantic Scholar 喜欢 0 阅读量: 364 作者: MR Wenk 摘要: The crucial role of lipids in cell, tissue and organ physiology is demonstrated by a large number of genetic studies and by many human diseases that involve the disruption of lipid metabolic enzymes...
The Lipid Metabolites and Pathways Strategy (LIPID MAPS) initiative constitutes the first broad scale national exploration of lipidomics and is supported by a U.S. National Institute of General Medical Sciences Large Scale Collaborative "Glue" Grant. The emerging field of lipidomics faces many obstac...
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The emerging field of lipidomics 2005, Nature Reviews Drug Discovery Model systems, lipid rafts, and cell membranes 2004, Annual Review of Biophysics and Biomolecular Structure The state of lipid rafts: From model membranes to cells 2003, Annual Review of Biophysics and Biomolecular Structure Choleste...
The field of lipidomics sits in an interesting position as a more recently established sub-discipline of metabolomics, which is beginning to mature simultaneously with the advent of next-generation mass spectrometry instrumentation. Yet despite recent improvements in global lipidomics capabilities driven ...
The activity of the commensal microbiota significantly impacts human health and has been linked to the development of many diseases, including cancer. Gnotobiotic animal models have shown that the microbiota has many effects on host physiology, including
Identification of endogenous acyl amino acids based on a targeted lipidomics approach J. Lipid Res., 51 (2010), pp. 112-119 CrossrefView in ScopusGoogle Scholar [97] H.B. Bradshaw, N. Rimmerman, S.S.-J. Hu, S. Burstein, J.M. Walker Novel endogenous N-acyl glycines: identification ...
Establishment and maintenance of pregnancy depends on progesterone synthesized by luteal tissue in the ovary. Our objective was to identify the characteristics of lipid droplets (LDs) in ovarian steroidogenic cells. We hypothesized that LDs are a major f
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid