Adherent cell cultures are often dissociated from their culture vessel (and each other) through enzymatic harvesting, where the detachment response is monitored by an operator. However, this approach is lacking standardisation and reproducibility, and prolonged exposure or too high concentrations can affec...
The human immune system is composed of a distributed network of cells circulating throughout the body, which must dynamically form physical associations and communicate using interactions between their cell-surface proteomes1. Despite their therapeutic potential2, our map of these surface interactions rem...
Mesenchymal stem cells (MSCs) are a promising cell source for stem cell therapy of intractable diseases in veterinary medicine, but donor-dependent cellular heterogeneity is an issue that influences therapeutic efficacy. Thus, we previously established immortalized cells that maintain the fundamental proper...
The first important thing to know about PE files is that the executable file on disk is very similar to what the module will look like after Windows has loaded it. The Windows loader doesn't need to work extremely hard to create a process from the disk file. The loader uses the memory-...
The Windows loader doesn't need to work extremely hard to create a process from the disk file. The loader uses the memory-mapped file mechanism to map the appropriate pieces of the file into the virtual address space. To use a construction analogy, a PE file is like a prefabricated home....
the programmer explicitly associates the name of each externally visible procedure and data object with a numeric offset in the global vector; the linkage is accomplished in the compiled code by using these numeric offsets. B evaded this inconvenience initially by insisting that the entire program ...
DNA is about one million times denser than hard-disk storage; technically, one kilogram of DNA could store the entirety of the world's data (as of 2016).17 While these are early days, the scope and scale of these emerging capabilities could have...
Embryonic Timetable of Breast Development in the Human Age of Embryo (wk)Crown-Rump Length of Embryo (mean)Developmental Stage 42.5 mmMammary streak 52.5-5.5 mmMilk line, or milk ridge 65.5-11 mmParenchymal cells proliferate 7-811-25 mmMammary disk progresses to globular stage ...
1997b), the principal mechanism by which CRX controls OS biogenesis and disk renewal may be as a major regulator of the expression of many, if not all, OS proteins. The loss of CRX function imposed by the mutations may therefore critically reduce the synthesis of key OS proteins. The ...