Davis L, Hamner M, Bremner JD. Pharmacotherapy for PTSD: Effects on PTSD symptoms and the brain. In: Bremner JD, editor. Posttraumatic Stress Disorder: From Neurobiology to Treatment. Hoboken, NJ: Wiley-Blackwell (2016). p. 389-412.
Summary This chapter reviews pharmacotherapy for posttraumatic stress disorder (PTSD) and touches on the effects of medication on the brain. Benzodiazepines act on the gamma-aminobutyric acid (GABA)-benzodiazepine receptor complex and are associated with a reduction in anxiety. A range of antidepressant...
where a therapist helps the patient revisit traumatic memories. This new research suggests that this type of treatment can address PTSD by helping patients convert their traumatic memories, processed in the PCC, into sad memories, which are processed in the hippocampus. This allows patients to stop...
He couldn’t tolerate the standard treatments. Medications hadn’t made much difference and left him with intolerable side effects. The kind of talktherapyknown to work in PTSD required him to intentionally remember his horrifying childhood, a mental activity he understandably wanted to a...
OBJECTIVE: The authors used a low-dose dexamethasone suppression test to examine the effect of a PTSD risk factor, parental PTSD, on cortisol negative feedback inhibition in adult offspring of Holocaust survivors with PTSD (N=13) versus without PTSD (N=12) as well as a comparison group of ...
These effects were partially blocked by pretreatment with prazosin but completely prevented by ACH-000029. Collectively, these findings contribute to the brain-wide characterization of neural circuits involved in PTSD-related stress responses. Furthermore, the identification of brain areas regulated by ACH...
Research in animals and humans has revealed some of the structural, functional and molecular changes in the brain that underlie the effects of stress on social behaviour. Findings in this emerging field will have implications both for the clinic and for society. This is a preview of subscription...
One common sign of complex PTSD is an intensely critical inner voice that just won't get off your back. 复杂性创伤后应激障碍的一个常见迹象是,内心有非常强烈的批评声音,就是一直环绕着你。 You know the one, that says things like: "You're useless. You've achieved nothing." ...
This randomized clinical trial investigates the effects of exercise on brain health indicators, including intelligence, executive function, academic
Future primary studies aimed at investigating the effects of PTSD on GWI should aim to use a clinical diagnosis of PTSD. Another limitation related to this is the lack of comparison to a PTSD cohort without GWI. Again, this stems directly from the secondary analysis nature of this study. ...