The effects of meta-chlorophenylpiperazine at cerebral blood flow and behavior in Obsessive Compulsive Disorder (OCD). Is the cerebellum involved in OCD?For the characterization of the human cytochrome P450 enzymes involved in the in vitro metabolism of mirtazapine, [3H]-mirtazapine was incubated at...
Obsessive-Compulsive Disorder (OCD) often begins in childhood and significantly impacts family, social, and academic functioning of OCD-affected youth. Despite children spending most of their waking hours at school, evidence about the effects of OCD on school functioning is limited. Parents of OCD-...
Currently, different combinations of rTMS strategies exist for OCD treatment with no consistent opinion3,10. The most common strategies include (1) LF-rTMS or HF-rTMS applied over the dorsolateral prefrontal cortex (DLPFC); (2) LF-rTMS applied over the supplementary motor area (SMA); (3) LF...
摘要: This treatment does not have any negative effects on partners.Partners show improvements in relationship functioning in the short-term.Partners show reductions in their criticalness in the short-term.Partners experience both short- and long-term gains in communication....
While these two disorders are distinct, there’s no denying that there’s also a significant link between the two, with similar symptoms. Treatment can be difficult, especially for those who have both disorders. With the co-occurrence of these disorders, the effects and symptoms of OCD are of...
Methods: We studied the behavioural effects of m-CPP on tics, obsessions, compulsions and impulsions of GTS. Twelve medication-free GTS patients (ten men, two women) were included in a single dose 0.5 mg/kg oral m-CPP challenge study with a double-blinded placebo-controlled cross-over ...
were in lockdown at home for six continuous weeks, when the adverse psychological effects on children and teenagers are yet to be determined. In this regard, the data in China indicate that the consequences on the levels of depression during quarantine were greater in teenagers than in adults2...
The 21-item Depression Anxiety Stress Scales (DASS-21) will be used to measure the impact of the programme on parent/caregiver distress, while the Family Accommodation Scale (FAS) will be used to measure change in family accommodation of OCD symptoms. Multilevel mixed effects linear regression ...
The COVID-19 pandemic has had deleterious effects on the mental health of the general population across the globe including increased anxiety (Huang & Zhao,2020), post-traumatic stress symptoms and an acute stress reaction (Liu et al.,2020), as well as increased suicidal ideation and attempts...
effects. Psychiatric disorders are now known to be highly polygenic—that is the genetic component includes hundreds or thousands of individual rare and common variants. The large majority of common risk alleles will not show genome-wide significant evidence of association given available sample sizes....