The effects of ketamine on cognitive function in eld- erly patients undergoing ophthalmic surgery: a pilot study [ J]. Anesth Analg,2016,122(4) :969-975.DOI: 10.1213/ANE.Rascon-Martlnez DM, Fresan-Orellana A, Ochardn-HemcindezME,et al.The effects of ketamine on cognitive fu...
Objective To investigate the effects of ketamine on the percentage ofθband power in quantitative pharmaco-electroencephalogram(QPEEG).Methods Twenty male healthy volunteers were randomly divided into two groups.The EEG samples were obtained before and at regular intervals following various ketamine injectio...
Ketamine, an N-methyl-D-aspartic acid receptor antagonist that was first discovered in 1962, has become established in anaesthesia providing dose-dependent anaesthetic, sedative, and analgesic effects. Ketamine, however, also acts on a wide range of other cellular targets, resulting in interesting an...
Background and Purpose The effects of ketamine in attenuating morphine tolerance have been suggested to result from a pharmacodynamic interaction. We studied whether ketamine might increase brain mo...
In the current study, we sought to explore this further using a psychopharmacological study of the effects of ketamine – a drug model of early schizophrenia – on intentional binding. Ketamine is a non-competitive NMDA receptor antagonist, which, at sub-anaesthetic levels, produces a state in ...
In horses, the combination of xylazine with ketamine has been shown to produce short periods of surgical anaesthesia characterized by a smooth induction and a rapid, quiet recovery 2,5 . This paper describes the cardio-vascular effects of this combination and compares them with the combination of...
It is not clear whether ketamine attenuates neostigmine-induced airway smooth muscle contraction by inhibiting the PI response. This study was designed to examine the effects of ketamine on neostigmine-induced contractile and PI responses of the rat trachea.Methods. Thirty male Wistar rats weighing ...
The Effects of Small-Dose Ketamine on MorphineConsumption in Surgical Intensive Care Unit Patients AfterMajor Abdominal SurgeryNicolas Guillou, MD* , Miche`le Tanguy, MD* , Philippe Seguin, MD* , Bernard Branger, MD† ,Jean-Pierre Campion, MD‡ , and Yannick Malle´dant, MD**Surgical In...
This study was designed to investigate the effects of ketamine, an N-methyl-D-aspartate receptor antagonist, on the development of tolerance to morphine and morphine antinociception during intrathecal infusion. Two intrathecal catheters were implanted in the subarachnoid space in male rats under pentob...
Objective To investigate the effect of ketamine(KT)on the hypnosis of propofol(P)as an experimental work to support the clinical use of compound anesthesia of KT and P.Methods Mice in 3 groups(P group,KT group and P+KT group,n=10 each)were given the two drugs singly or in combination ...