Kristensen ML,Christensen PM,Hallas J,et al.The effect of statins on average survival in randomised trials,an analysis of end point postponement [J].BMJ Open,2015,5(9):118-136.Kristensen ML, Christensen PM, Hallas J. The effect of statins on average survival in randomised trials, an ...
Prior studies have shown an anticancer effect of statins in patients with certain malignancies. However, it is unclear whether statins have a mortality benefit in lung cancer. We compared survival of patients with stage IV non-small cell lung cancer (NSCLC) receivingvs. not receiving statins prior...
In patients with HF (and reduced or preserved ejection fraction), the prescription of statins did not appear to be associated with better survival after 1year of follow-up in the EPICAL2 cohort. We cannot exclude that a subpopulation of HF patients may have some benefits compared with the ...
Sensitivity and scenario analyses were performed to assess the effect of parameter uncertainty on model robustness. Results When used in conjunction with SoC, finerenone extended time free of CV events and renal replacement therapy by respectively 0.30 and 0.31 life years compared to SoC alone, ...
Cardiovascular disease (CVD) remains the leading cause of death globally and an ageing world population is expected to increase the burden of CVD further. Among older adults, CVD is also a major cause of disability, functional decline, loss of independen
Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis BMJ, 326 (2003), pp. 1407-1408 Google Scholar 7 Y. Cui, R.S. Blumenthal, J.A. Flaws, et al. Non–high-density lipoprotein cholesterol level as a ...
In this survival meta-analysis, the TTB to prevent 1 MACE for 100 adults aged 50-75 years treated with statins was 2.5 years. These results suggest that statins are most likely to benefit adults aged 50-75 years with a life expectancy of greater than 2.5 years and less likely to benefit...
We aimed to investigate the effect of thyroid hormone administration on the risk of second primary cancer in patients who underwent thyroidectomy for differentiated thyroid cancer. Data were extracted from the medical billing data of the Health Insurance Review and Assessment Service in South Korea. Pa...
We observed no evidence for any statistical effect-modification or interaction, although rates of dyslipidaemia were highest amongst women with an AB blood-group who smoked. The strengths of this study include its prospective design, large number of participants and cases, control for several ...
CHD patients have significantly lower concentration of the large, LpA-I α-1 HDL particles compared to controls. Our data indicate that statins which are the most effective in lowering LDL-C and TG are also the most effective agents in modifying the HDL subpopulation profile in CHD patients ...