We emphasize Type I interferon response and the strategies of evading innate immune defense used by SARS-CoV-2. We also extensively discuss the cells and their function involved in the innate immune response and inflammatory response, as well as the promises and challenges of drugs targeting ...
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Antiarrhythmic drugs are compounds which influence the electrical activity of the heart and may thereby alter or abolish the abnormalities in impulse initiation and conduction which cause cardiac arrhythmias. Until the early 1960s only two drugs, quinidine and procainamide, were used widely as antiarrhyt...
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To the best of our knowledge there is no study comparing the effects of ciprofloxacin and vancomycin addition in bone cement. These drugs have similar water solubility but different molecular weights. The purpose of this study was to investigate mechanical properties of cement impregnated with these ...
Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Transl Psychiatry. 2012;2:e94. Article CAS PubMed PubMed Central Google Scholar Patel S, Hill MN, Cheer JF, Wotjak CT, Holmes A. The endocannabinoid system as a target for novel anxiolytic drugs. ...
G-protein-coupled receptor kinases (GRKs) phosphorylate the agonist-bound receptor, which can subsequently bind to arrestin and be either internalized or signal through the MAP kinase and other pathways. (B) The β2AR exhibits basal agonist-independent activation of Gs. Drugs that can suppress ...
Effect of drugs on the risk of injuries in children with attention deficit hyperactivity disorder: a prospective cohort study. Lancet Psychiatry 2, 702–709 (2015). Article PubMed Google Scholar Chang, Z., Lichtenstein, P., D’Onofrio, B. M., Sjolander, A. & Larsson, H. Serious ...
2 Division of Physical Activity and Weight Management, University of Kansas Medical Center, Kansas City, KS 66160, USA 3 Department of Cellular Biology and Physiology, Brigham Young University, Provo, UT 84602, USA 4 Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT ...