The NHGRI-EBI GWAS Catalog serves as a vital resource for the genetic research community, providing access to the most comprehensive database of human GWAS results. Currently, it contains close to 7 000 publications for >15 000 traits, from which more than 625 000 lead associations have been ...
OTG links were parsed to determine the source of each OTG data point: the EBI GWAS catalog30 (n = 136,503 hits with L2G share ≥0.5), Neale UK Biobank (http://www.nealelab.is/uk-biobank; n = 19,139), FinnGen R6 (ref. 31) (n = 2,338) or SAIGE (n =...
GWAS Catalog: https://www.ebi.ac.uk/gwas/ Online Mendelian Inheritance of Man (OMIM): https://www.omim.org Supplementary information Supplementary Information Glossary Genome-wide association studies (GWAS). A study that involves genotyping large numbers of participants to identify statistical asso...
K. GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. eLife 10, e58615 (2021). Article CAS PubMed PubMed Central Google Scholar Buniello, A. et al. The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted ...
The EBI GWAS catalog was used to determine the number of total GWASs reported from 2005 through the end of 2016, which are shown in blue. The number of post-GWAS functional studies reported each year were also identified (orange line) by (1) reviewing the titles, and in some cases, abs...
1a–c). GWAS data curated in the NHGRI-EBI GWAS Catalog (V1.0.2) also indicated association with carotid intimal-medial thickness (IMT), with the A allele identified as promoting disease risk for both CAD and IMT31,32,33,34. Rs2019090 was shown to serve as an expression quantitative ...
Additional Contributions: The Program in Complex Trait Genomics (https://cnsgenomics.com/content/data), GWAS Catalog (https://www.ebi.ac.uk/gwas/), the Psychiatric Genomics Consortium (https://www.med.unc.edu/pgc/), Regensburg GEM Platform (https://www.uni-regensburg.de/medizin/epidemiologie...
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019 Nucleic Acids Res, 47 (2019), pp. D1005-D1012 CrossrefView in ScopusGoogle Scholar [68] M. Kanai, M. Akiyama, A. Takahashi, et al. Genetic analysis of quantitative traits ...
Additional GWAS information is available at the GWAS catalog managed by the European Bioinformatics Institute: https://www.ebi.ac.uk/gwas/. Original gene expression and mutation data are available at the TCGA via the Genomics Data Commons. https://gdc.cancer.gov/. Conflicts of Interest: The ...
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Res. 2017, 45, D896–D901. [CrossRef] [PubMed] 55. Consortium, G.T. Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans. Science ...