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We observed intestinal RorcGFP+ ILC3s and a larger population of ActbECFP+ lymphocytes within the intestinal villi (Fig. 1a and Supplementary Video 1). ActbECFP+ lymphocytes exhibited diverse in vivo dynamics, ranging from immobility to rapid migration (Fig. 1b,c), which likely reflected ...
A. et al. Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect. Immun. 77, 2367–2375 (2009). Article CAS PubMed PubMed Central Google Scholar Dethlefsen, L., Huse, S., Sogin, M. L. & Relman, D. A. The pervasive effects of an ...
原论文的链接:Differential Dynamics of the Maternal Immune System in Healthy Pregnancy and Preeclampsia 1.问题的设定 作者使用了21 immune cell types作为实验的特征. 样本总数是23个,其中为preeclampsia的11个,另外12个是normotensive. 2. correlation Network 这里应该是相关关系,作者可能在分析特征间的相关关系。
These studies have leveraged a combination of compositional and functional attributes to identify a broad trend of long-term retention of one’s individual strains over time, even at the SNV level. To understand community dynamics of healthy human skin, we investigated the temporal stability and ...
Skin and Hair Wound Healing Kidney Liver Pancreas Adipose and Connective Tissue Early Embryo Endothelial Cells and Hemangioblasts Epithelial Germline Hematopoietic System Placenta and Umbilical Cord Derived Cells Pluripotent Stem Cells Preclinical Study and Clinical Applications ...
Rage ligands derived from cancer cells can also support the establishment of a pro-tumorigenic microenvironment by activation of leukocytes, vascular cells, fibroblasts, and modulation of immune tolerance [11]. Although multiple intracellular signaling pathways, including MAP kinases, Rho GTPases, PI3K,...
Aastrom Biosciences has developed a proprietary cell-processing technology that enables the manufacture of ixmyelocel-T, a patient-specific multicellular therapy expanded from a small sample of a patient's own bone marrow. Ixmyelocel-T is produced under
The cutaneous immune system modulates colonization by the microbiota and is also vital during infection and wounding. Dysregulation of the skin immune response is evident in several skin disorders. A wide range of skin disorders are postulated to arise in part owing to a microbial component. These...
The crosstalk between the nerve and stomatognathic systems plays a more important role in organismal health than previously appreciated with the presence of emerging concept of the “brain-oral axis”. A deeper understanding of the intricate interaction between the nervous system and the stomatognathi...