Which of the following is found in RNA but not in DNA? (a) The five-carbon sugar ribose (b) Nitrogenous bases (c) A sugar-phosphate backbone (d) Phosphate groups (e) Nucleotides. Which of the following is not a component within a single ...
Second, the number of ways of choosing which of these numerous weak interactions to incorporate into a single binding protein is combinatorially large, and any given protein backbone is unlikely to be able to simultaneously present side chains that can encompass any preselected subset of these ...
We sequenced genomic DNA isolated from field-collected N. clavipes females and used a combination of strategies to de novo assemble 2.44 Gb of genome (Table 1, Supplementary Tables 1–4, and Supplementary Note). The predicted size of the entire N. clavipes genome is 3.45 Gb, with 55% estim...
What makes the backbone of DNA? a. nucleic acids b. phosphoric acid c. deoxyribose sugar d. phosphoric acid and deoxyribose sugar Show how uracil can form strong hydrogen bonds to adenine, just as thymine can. Which of the following is found in ...
The absence of orthogonal aminoacyl-transfer RNA (tRNA) synthetases that accept non-l-α-amino acids is a primary bottleneck hindering the in vivo translation of sequence-defined hetero-oligomers and biomaterials. Here we report that pyrrolysyl-tRNA synthetase (PylRS) and certain PylRS variants ac...
͑B͒ The formation of a mercaptohexanol ͑MCH͒ monolayer that prevents contacts between the DNA backbone and the substrate, the HS-ss-DNA is left at- tached by the thiol end. ͑C͒ The end-tethered HS-ss-DNA is shown after hybridization to complementary oligonucleotides. ͓...
However, nowadays it is clear that the backbone must be considered as an active dynamic element while defining the conformational properties of double-helical DNA [34, 61-69]. The main role of the backbone is in restricting the conformational space available for the placement of bases, and in...
In a recent study, the same group designed highly functionalized nucleic acid polymers (HFNAPs) assembled by ligase-mediated DNA-templated polymerization, starting with 32 building blocks that contain diverse side chains on a DNA backbone [196]. Repeated evolution cycles of polymer translation, ...
Multidrug resistance (MDR) is the major cause, by which cancer cells expel the drugs out, developing a challenge against the current chemotherapeutic drugs regime. This mechanism is attributed to the over expression of ABC transporters like MRP1 on the surface of cells. Since nucleotide binding do...
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However, the presence of BBB complicates the pharmacotherapy for CNS disorders as the most chemical drugs and bioph