Distribution patterns are significantly heterogeneous when variable diffusion coefficients associated with plaque compositions are used to model drug transport. The area under concentration (AUC) and peak concentration for free sirolimus decrease as time progresses from 1 to 4 h (cf. Fig.5a–c), but ...
One of a large class of complex organic chemical compounds that are essential for life. Proteins play a central role in biological processes and form the basis of living tissues. They consist of long, looping or folding chains of smaller compounds called amino acids. Enzymes, antibodies, and he...
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(redirected from attachment plaque)Also found in: Thesaurus, Medical, Legal, Financial, Encyclopedia. at·tach·ment (ə-tăch′mənt) n. 1. The act of attaching or the condition of being attached. 2. Something, such as a tie, band, or fastener, that attaches one thing to ...
respectively.267It is a suitable approach for quantitative and reliable estimation of lipid compositions of core plaque, however, NIRS is not capable of detailed and complete plaque morphological assessment as well as visualization and evaluation of lumen, vessel wall dimensions, and plaque burden.268...
Fasudil treatment reduced Aβ plaque deposition and phosphorylated tau tangles in the hippocampus. (A) Aβ1-42 plaques was checked in the hippocampus of the mice in each group. (a–c) WT, (d–f) ADNS, (g–i) ADF. Immunofluorescent intensity quantification of anti-Aβ1-42 showed signifi...
Engel A, Aebi U, Kistler J: Polymorphic fibrillar assembly of human amylin. J Struct Biol 119:17-27, 1997). Amylin is known to form amyloid fibers leading to the formation of water-insoluble plaque. Consequently, it has been necessary to develop an analog to solve these solubility problems...
infrarenal aorta in 67 male cadaver aortas were studied. The results indicate that there may be different local responses to atherosclerosis in humans. Plaque deposition with local dilation, thinning of the middle membrane, and loss of the medial elastic plate may predispose this aorta to subsequent...
These observations suggest that the mitochondrial ETC is critical for the increase in superoxide. However, this increase was traced to ER-localized NOX. There is an unusual redox cycle capable of combining oxidative folding with ROS accumulation in the ER. ER protein folding ability is regulated ...