as total ctDNA levels have been demonstrated to be related to tumor mass size in many types of tumors, including NSCLC [100,101]. Further, ctDNA has shown potential clinical predictive value for patients with NSCLC in different disease states. Studies of NSCLC ...
These stressors reduce the activity of the complex network that regulates proteostasis and the integrity of the proteome. Diseases such as AD, Parkinson’s disease and cataracts are caused by the misfolding and accumulation of aggregated proteins, which mostly affect postmitotic cell types such as ...
E. et al. A pooled analysis of individual patient data from National Clinical Trials Network clinical trials of concurrent chemoradiotherapy for limited-stage small cell lung cancer in elderly patients versus younger patients. Cancer 125, 382–390. https://doi.org/10.1002/cncr.31813 (2019). ...
many drugs are being examined targeting pathways involved in the pathogenesis of NF2 [14,94,143]. In this section, clinical trials evaluating the targeted therapies for NF-related tumors are discussed (Fig.3, Table3
The Neurostatus-eEDSS® is the standard assessment deployed in MS randomized clinical trials (RCT), typically serving as the primary endpoint. COVID-19 pandemic has impacted conduct clinical studies. This opened opportunities to adapt the data capture systems in clinical trials i.e., conducting ...
Background: Logistics management in the clinical trials industry is a very challenging undertaking because it involves multiple stakeholders, complex processes, diverse software applications, intensive white-collar jobs, and onerous quality standards. Current business practices are inefficient and difficult to...
Given the dearth of clinical trials, the level of evidence is low for the surgical treatment of complicated liver CE and disseminated CE (Dziri et al., 2004). Standardized terminology and procedures should be agreed upon by surgeons for the techniques to be compared. The risks include those ...
(855) 404-4592 karen@asbestos.com Karen Selby is a registered nurse and Board Certified Patient Advocate with over 30 years of experience and a background in oncology and thoracic surgery. She previously served as the regional director of a tissue bank and assisted with thoracic surgeries as an...
In addition to the aforementioned active clinical trials, there is a competition between those in pre-clinical for entering the clinic. Imperial College London, which has developed a ”self-amplifying” RNA vaccine with the aim of boosting the production of a viral protein to stimulate the immune...
The criteria for discharge were absence of fever for at least 3 days, substantial improvement in both lungs on chest computed tomography (CT), clinical remission of respiratory symptoms and comorbidities, and cessation of SARS-Cov-2. Statistical analysis Continuous variables were compared using the ...