S. epidermidis and other common PC contaminants form surface-attached communities of matrix-embedded cells, known as biofilms, during PC storage. Biofilms are formed by bacteria adhering to either platelet cells or to the plastic of PC containers. Bacterial adhesion to PC containers is enhanced by...
Design, Setting, and Participants University hospital dermatologic clinic study involving the environmental component related to the characterization, correlation, and impact of staphylococci and their biofilms in AD. We processed routine skin swabs from lesional and nonlesional skin from 40 patients with ...
Discusses biofilm pathogenesis and defines some clinical criteria for classifying infections with a biofilm aetiology. Article CAS PubMed Google Scholar Donlan, R. M. & Costerton, J. W. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 15, 167–193 (2002...
Bacterial biofilms are often defined as communities of surface-attached bacteria and are typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas aeruginosa. However, it has become evident that this is not how all biofilms develop, especially in vivo, in clinical and in...
Whilst these mechanisms undoubtedly make a major contribution to antibiotic failure in the clinic, the phenomenon of clinical failure in spite of sensitivity in laboratory tests is also well recognised. It is in this context that attention has focussed on bacteria growing as adherent biofilms, not ...
exhibit dramatically decreased susceptibility to antimicrobial agents and resistant to the host immune clearance, which increases the difficulties for the clinical treatment of infections [9,10,11]. Furthermore, the antimicrobial arena is experiencing a shortage of lead compounds, and growing negative con...
nanoparticles for biofilm-associated infection therapy.###Biofilm matrix-degrading enzymes.###Animal models to evaluate bacterial biofilm development.###Imaging bacteria and biofilms on hardware and periprosthetic tissue in orthopedic infections.###Field emission scanning electron microscopy of biofil 来自 ...
This study reveals that phenazine production alters both the metabolic profile of biofilms and their tolerance to different classes of clinical antibiotics, suggesting that beyond induction of specific cellular defences, secondary metabolites can also affect antibiotic susceptibility via indirect mechanisms. ...
The Bayon temple in Angkor Thom, Cambodia has shown serious deterioration and is subject to the formation of various pigmented biofilms. Because biofilms are damaging the bas-reliefs, low reliefs engraved on the surface of sandstone, information about the microbial community within them is indispensabl...
Bacterial antibiotic resistance is a global health concern of increasing importance and intensive study. Although biofilms are a common source of infections in clinical settings, little is known about the development of antibiotic resistance within biofi