However, as early as 1945, Sir Alexander Fleming expressed concern about the consequences of antibiotic overuse. Seven decades later, antimicrobial resistance (AMR) has reached alarming levels and is now a major public health threat in the twenty-first century. The emergence of multidrug-resistant ...
The world's highest mortality rate from antimicrobial resistance infection is observed in Africa. To alleviate such life-threatening challenge, One Health strategies like effective communication, education, training, surveillance, detection and joint effort across disciplines and sectors are urgently needed....
Most recently, Tillotson was a member of the Scientific Steering Committee for the International Society of Chemotherapy's Symposium on Clostridium difficile in Leipzig, Germany. Here, he talks with Expert Review of Clinical Pharmacology about the challenge of antibiotic resistance from an industry ...
Although the clinician anticipates a significant challenge when treating infections caused by P. aeruginosa and A. baumannii, K. pneumoniae is exhibiting an ever-widening spectrum of antibiotic resistance. In this review, we will illustrate the varied β-lactam resistance mechanisms that pose the ...
Antibiotic prophylaxis: problems in paradise Drug Resistance, MicrobialEndocarditis, BacterialHumanMouth DiseasesRisk FactorsSepticemiaThe age of antibiotic prophylaxis may be receding into its twilight years... TJ Pallasch - 《Dent Clin North Am》 被引量: 284发表: 2003年 ...
51. Larger clinical studies are needed to determine the degree to which tolerance plays a role in treatment failures. In addition, understanding how the complex circuitry that allows cells (or only some cells) to grow under stress conditions is an important challenge currently being explored with...
The challenge of compound aggregation producing false positives during HTS campaigns has been demonstrated by Shoichet and co-workers18. We routinely examine the Hill slopes of our inhibition fits because false positives due to aggregation tend to have abnormally high Hill slopes. The Hill Slopes for...
Define Antibiotic resistance. Antibiotic resistance synonyms, Antibiotic resistance pronunciation, Antibiotic resistance translation, English dictionary definition of Antibiotic resistance. n. A substance, such as penicillin or erythromycin, produced by
A. The continuing challenge of ESBLs. Curr. Opin. Pharmacol. 7, 459–469 (2007). Article CAS PubMed PubMed Central Google Scholar Potter, R. F., D'Souza, A. W. & Dantas, G. The rapid spread of carbapenem-resistant Enterobacteriaceae. Drug Resist. Updat. 29, 30–46 (2016). ...
Antibiotic resistance and defensive medicine, a modern challenge for an old problem: the case of Ureaplasma urealyticum. 来自 Semantic Scholar 喜欢 0 阅读量: 29 作者:GA Messano,F Cancrini,LT Marsella 摘要: The practice of defensive medicine is an emerging problem in public health. A common ...