Associative learning during delay eyeblink conditioning (EBC) depends on an intact cerebellum. However, the relative contribution of changes in the cerebellar nuclei to learning remains a subject of ongoing debate. In particular, little is known about the changes in synaptic inputs to cerebellar nucl...
Fluorescent PCR products obtained following the second amplification and corresponding to standard isoforms and samples were added to a mixture of ROX-labeled migration standards (MWG-BIOTECH, AG; 0.5 μl each) covering the whole range of the retention times required for CE single-stranded confor...
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The cerebellum is a brain structure involved in motor and cognitive functions. The development of the cerebellar cortex (the external part of the cerebellum) is under the control of numerous factors. Among these factors, neuropeptides including PACAP or somatostatin modulate the survival, migration ...
Every sixth section was retrieved and plated to encompass the entire brain from the olfactory bulb to the cerebellum. Slides were air dried for 45 min, DAPI stained, cover slipped, and allowed to dry overnight. Full slides were scanned on the Aperio Scanscope FL at the Translational Pathology...
The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate...
Most of these studies demonstrate that the TLDc domain is essential for protection of neurons against oxidative and nitrosative stress-induced cell death, e.g. in mice cerebellum [3, 5, 12, 19, 23]. Other studies suggest that OXR1 could regulate glucose metabolism in mice cerebellum [23] ...
The suitability of the cerebellum as a reference region for nonspecific (11)C-MADAM binding could be confirmed, thus paving the way for experimentally less demanding approaches, such as the simplified reference tissue model, for applied clinical studies. 展开 ...
In brief, brains without cerebellum and olfactory bulb from 3xDR and control mice were harvested and cut into 1-mm-thick sections using stainless steel brain matrices. Next, brain slides were incubated in 95% O2 and 5% CO2 bathed choline chloride solution (92 mM choline chloride, 2.5 mM...
Recent research has shown that the cerebellum is involved not only in motor control but also in higher-level activities, which are closely related to creativity. This study aimed to explore the role of the cerebellum in visual divergent thinking based on