Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer Genome Consortium (ICGC) and The Cancer Genome At...
Chemotherapy combined with immunotherapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for pancreatic ductal adenocarcinoma (PDAC). We conducted a randomized phase 2 trial evaluating the efficacy of nivolumab (
https://ror.org/04twxam07grid.240145.60000 0001 2291 4776Department of Palliative, Rehabilitation, and Integrative MedicineThe University of Texas MD Anderson Cancer Center Houston TX USASanthosshi Narayananhttps://ror.org/04twxam07grid.240145.60000 0001 2291 4776Department of Palliative, Rehabilitation...
In addition to social workers, financial consultants and other common cancer center support services, the Hospital of the University of Pennsylvania also has semi-private, private and deluxe accommodations, ideal for patients and families that are traveling for mesothelioma treatment. They also offer ho...
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Center for Eye Disease & Development, School of Optometry & Vision Science Program, University of California Berkeley, Berkeley, CA 94720-2020, USA Purpose Interest in the mechanisms underlying eye growth regulation has risen steeply with the rapid rise in the prevalence of myopia, as an example...
it is also necessary to define the radius of the clump, so that its size can be determined. For this, XCVATR makes use of the scale parameter at which the clump is identified (i.e., σaat scalea). Thus, all cells that are closer thanσato the center of a given clump are assigne...
31. National Cancer Center, Tokyo 104-0045, Japan. 32. German Cancer Aid, Bonn 53113, Germany. 33. Division of Cancer Genomics, National Cancer Center Research Institute, National Cancer Center, Tokyo 104-0045, Japan. 34. Laboratory of Molecular Medicine, Human Genome Center, ...
Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, USA Qingbo Wang, Ryan L. Collins & Jack A. Kosmicki Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA Ryan L. Collins, Harrison Brand, Michael E. Talkowski, Sekar Kathiresan & ...
Lynda Chin from University of Texas MD Anderson Cancer Center, and Dr. Jasmine Zhou from University of Southern California. "Single-Cell Analysis of Tumor Heterogeneity" Intratumor heterogeneity is a critical impediment to improving prognosis of many types of cancer such as breast and prostate cancer...