containing an antiproliferative drug to inhibit intimal hyperplasia (IH) caused by abnormal growth of smooth muscle cells (SMCs) present intunica media1,2,3,4,5. DCBs have revolutionised the treatment of restenosis at the sites of grafting or ISR...
between different states, how adult stem cells are maintained and differentiate, at unprecedented resolution. The resulting advances in our understanding of stem cell and developmental biology have opened the door to the engineering of complex tissues and the use of stem cells for therapeutic purposes...
Lung cancer is the leading cause of cancer-associated mortality worldwide1. Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACERx study. This project aims to decipher lung ...
The accumulation of senescent cells is closely related to aging. Senescent cells are a class of cells that undergo irreversible cell cycle arrest following cellular stress or injury. Despite ceasing division, these cells remain metabolically active and exhibit pro-inflammatory characteristics [4]. System...
Stem cells that have undergone long-term ex vivo expansion are most likely functionally compromised (namely cellular senescence) in terms of their stem cell properties and therapeutic potential. Due to its ability to attenuate cellular senescence, melatonin (MLT) has been proposed as an adjuvant in...
The theory of star-planet coevolution chapter 2 the author: Wei Ju (琚伟) The Theory of Star-Planet Coevolution Chapter 2 The Origin and Evolution of the Solar System – Stellar Merger Model 2.1 The philosophical inspiration of the Yin-Yang dialectics of Taoism and the holistic view of TCM...
Additionally, passive prostheses are generally lighter than active devices, because they contain no motors and few mechanical systems. To close the gap in function, some passive hands include multi-positional joints; these are termed adjustable passive prostheses [2]. Using the intact hand, or by ...
However, when contact is established with a recipient, pilus retraction draws the cells together, resulting in the formation of a mating pair [69]. In liquid culture, the pili mediate the formation of larger mating aggregates that contain donor and recipient cells in tight wall-to-wall contact...
Adipose-derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) isolated from adipose tissue. They possess remarkable properties, including multipotency, self-renewal, and easy clinical availability. ADSCs are also capable of promoting tissue regeneration through the secretion of var...
They even communicate, and are lined, and externally wrapped together, by the same membrane; the whole assuming a pear-like form, attached by its base or greater extremity, and decreasing in size as it proceeds downwards; the cells becoming fewer, and terminating at length in a kind of ...