Storey, which appeared in a 2002 issue of the 'Journal of Cellular Biology.' Effect of HSV-1 infection on the membrane expression of sodium channels; Use of voltage-clamp techniques.doi:10.1038/nrn975López, Juan CarlosNature Reviews Neuroscience...
The action potential of the squid giant axon is formed by just two voltage-dependent conductances in the cell membrane, yet mammalian central neurons typically express more than a dozen different types of voltage-dependent ion channels. This rich repertoire of channels allows neurons to encode infor...
Between signals, the neuron membrane’s potential is held in a state of readiness, called theresting potential. Like a rubber band stretched out and waiting to spring into action, ions line up on either side of the cell membrane, ready to rush across the membrane when the neuron goes active...
Develop from membrane, beginning with the assembly of proteins that form coats( form rigid cage-like structures/ select the protein cargo) Arrived at the cis cide of the Golgi complex, fuse with its membrane to deliver their content Veticles( soluble and membrane-bound proteins/ srcretory prote...
We next investigated whether the inflammatory response is a side effect of learning-induced DNA damage or whether it contributes to memory formation. We induced a neuron-specific knockout of TLR9 in CA1 dorso-hippocampal neurons of Tlr9fl/fl mice by locally injecting adeno-associated virus (AAV9...
The mammalian brain consists of millions to billions of cells that are organized into many cell types with specific spatial distribution patterns and structural and functional properties1–3. Here we report a comprehensive and high-resolution transcripto
The immunoreactivity of the neuronal enzyme, γγ-enolase (neuron-specific enolase), was also decreased, but to a lesser extent than glutamine synthetase. Pre-incubation of the slices with L-methionine- S -sulphoximine (500 μM), an irreversible inhibitor of both glutamine synthetase and γ-...
ByNeuronicus, 25 January 2017 The FIRSTS: The Name of Myelin (1854) One reason why I don’t post more often is that I have such a hard time deciding what to cover (Hint: send me stuff YOU find awesome). Most of the cool and new stuff is already covered by big platforms with fu...
M. The problem of neuronal cell types: a physiological genomics approach. Trends Neurosci. 29, 339–345 (2006). Article CAS PubMed Google Scholar Seung, H. S. & Sumbul, U. Neuronal cell types and connectivity: lessons from the retina. Neuron 83, 1262–1272 (2014). Article CAS Pub...
Topological defects determine the structure and function of physical and biological matter over a wide range of scales, from the turbulent vortices in planetary atmospheres, oceans or quantum fluids to bioelectrical signalling in the heart1,2,3 and brain4, and cell death5. Many advances have been...