Dysregulation of cell cycle signaling is a pathognomonic feature of tumor initiation and progression. An understanding of the key cell cycle components dysregulated in cancer and the molecular mechanisms responsible has led to the generation of new targe
Cyclins, cyclin-dependent kinases and other components of the core cell cycle machinery drive cell division. Growing evidence indicates that this machinery operates in a distinct fashion in some mammalian stem cell types, such as pluripotent embryonic stem cells. In this Review, we discuss our curre...
The Cell Cycle: Gene Enzyme Interactions presents the primary regulatory mechanisms of the cell cycle. This book provides theoretical and methodological discussions concerning cell cycles. Organized into 17 chapters, this book begins with an overview of cell evolution and thermodynamics. This text then ...
Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimu latory role of a variety of mesenchymal cell activators and inhibi tory role of TGF-β Blood, 75 (1990), p. 96 View PDFView articleView in ScopusGoogle Scho...
【英文原版】Molecular Biology of the Cell细胞分子生物学第6版 pdf epub mobi txt 电子书 下载 具体描述 编辑推荐As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and ...
8 the cell cycle: gene enzyme interactions presents the primary regulatory mechanisms of the cell cycle. this book provides theoretical and methodological discussions concerning cell cycles. organized into 17 chapters, this book begins with an overview of cell evolution and thermodynamics. this text ...
细胞周期调控定 Regulation of the cell cycle.ppt,cyclinB ↓ APC 降解 ↓ MPF解聚、失活 组蛋白去磷酸化 ↓ 染色体去凝集 核纤层蛋白去磷酸化 ↓ 核膜组装 核形成 肌球蛋白去磷酸化 ↓ 收缩环溢缩、分裂沟加深 胞质分裂 MPF在细胞退出M期中的作用 检测点(checkpoint):
Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors. Dev. Cell 41, 129–142.e6 (2017). CAS PubMed PubMed Central Google Scholar Azzarelli, R. et al. Multi-site neurogenin3 phosphorylation controls pancreatic endocrine differentiation. Dev. Cell...
The Eukaryotic Cell Cycle 2024 pdf epub mobi 电子书 图书描述 The Eukaryotic Cell Cycle gives an overview of the stages of the eukaryotic cell cycle, as well as discussing important experiments, research, organisms of interest and findings connected to each stage of the cycle and the components ...
2c,d); cluster 9 as Epicardium_Mesothelial after previous annotation and broad epicardial gene expression; and cluster 10 as Epicardium_Proliferating with its expression of cell cycle and mitotic genes CENPF and HMGB2 (Fig. 2c). Interestingly, the Epicardium_FB-like cluster appeared to have low...