P53 is a genome-guardian protein and can lead to cell-cycle arrest and apoptosis once activated by DNA damage (Bieging et al., 2014; Levine et al., 1991; Vogelstein et al., 2000). Previous work has showed that HMGA1a can interact with P53 and inhibit its transcriptional function (...
Pacific Island Countries (PICs) are the center of origin and diversity for several root, fruit and nut crops, which are indispensable for food security, ru
function, it may be the case that a series of interactions are involved, with different genes being affected at different points in time (e.g. genes involved in cell cycle regulation). Similar issues arise when applying clustering algorithms to expression data, which also groups together genes w...
pneumophila modulates the host cell cycle to its advantage. The widely expressed enzyme sphingosine 1-phosphate lyase catalyzes the essentially irreversible cleavage of the signaling molecule sphingosine 1-phosphate, a product of sphingomyelin degradation that regulates cell prolifera- tion and cell death...
The bicluster also includescdc48a, which encodes a cell-division cycle – associated protein, with a strong match to the Bat UAS. We note that initial studies of the Bat UAS suggested that the regulatory sequences of as many as 108 genes contain instances of the motif [12]; clearly not ...
Learn biology Students also studied Study guides 11 Ruminant Fermentation I- Carbs 10 terms Population and environment 63 terms River Exe drainage basin - case study for drainage basin water cycle --> part 5 15 terms Biodiversity 45 terms ...
A significance level of 0.05 was considered, and statistical analyses were performed using GraphPad Prism 8. Results Effects of diets on renal parameters in animals with and without AKI We investigated the effects of AKI and/or diets on serum urea and creatinine in the rats. Two ...
Anammox and DNRA over the Omani Shelf MM Jensen et al Holmes RM, Aminot A, Kerouel R, Hooker A, Peterson BJ. (1999). A simple and precise method for measuring ammonium in marine and freshwater ecosystems. Can J Fish Aqaut Sci 56: 1801–1808. Jaeschke A, Hopmans EC, Wakeham SG,...
16.The method of claim 15, wherein the function or activity of the ring nuclease enzyme may be compared to a standard or normal level of ring nuclease activity or function. 17.17.-18. (canceled) Description: RELATED APPLICATIONS This application is a 35 U.S.C. § 371 national stage of ...
For example, the temporal activity of genes/proteins controlling progression through the cell cycle (in many different environmental conditions and cell types) can be viewed as a module. Moreover, since genetic regulatory systems are hierarchical [2], it is likely that these modules also interact ...