The Cancer Immunome Atlas:肿瘤免疫图谱数据库 肿瘤免疫疗法在多种恶性肿瘤的临床治疗上取得了显著效果,然而还是存在大部分患者对于免疫疗法没有响应的问题。为了更好的理解肿瘤和免疫细胞相互作用,科学家对来自TCGA和其他几个大型肿瘤研究项目,共20种实体瘤的NGS数据进行分析,对应文章链接如下 https://linkinghub./ret...
The Cancer Immunome Atlas:肿瘤免疫图谱数据库,欢迎关注”生信修炼手册”!肿瘤免疫疗法在多种恶性肿瘤的临床治疗上取得了显著效果,然而还是存在大部分患者对于免
The Cancer Immunome Atlas:肿瘤免疫图谱数据库 肿瘤免疫疗法在多种恶性肿瘤的临床治疗上取得了显著效果,然而还是存在大部分患者对于免疫疗法没有响应的问题。为了更好的理解肿瘤和免疫细胞相互作用,科学家对来自TCGA和其他几个大型肿瘤研究项目,共20种实体瘤的NGS数据进行分析,对应文章链接如下 https://linkinghub.elsev...
该数据库不仅可以查看TCGA中不同肿瘤的分析结果,其分析内容也值得我们借鉴,对于肿瘤样本的NGS数据, 可以进行基因表达与生存分析的关联分析,可以进行免疫细胞浸润分析,新抗原预测等分析内容。 关于“The Cancer Immunome Atlas数据库有什么用”这篇文章就分享到这里了,希望以上内容可以对大家有一定的帮助,使各位可以学到...
DIRAG, differentially-reactive antigens; CRC, colorectal cancer; GO, Gene Ontology. Comparison with the cancer immunome database To better understand the 671 unique DIRAGs identified in our microarray study (Table S1) in alignment with known tumor antigens, we compared our data with the Cancer...
To evaluate the distribution of macrophages in the TME, we firstly utilized gene set enrichment analysis (GSEA) via the cancer immunome database (TCIA)16. The results of the characterization of macrophages showed the heterogeneity across 19 solid cancers, and macrophages were enriched in stomach ad...
ontology KEGG Kyoto Encyclopedia of Genes and Genomes TMB Tumor mutation burden IPS Immunophenoscore TCIA The Cancer Immunome Database Supplementary Information The online version contains supplementary material available at https://doi.org/10.1186/s12859-023-05302-3....
We used data mining of the Cancer Immunome Database (CID), which comprises potential immunologic targets identified by serological screening of expression libraries. Candidate antigens were screened by DNA microarrays. Genes were then validated at the protein level by tissue microarrays, representing ...
Immunophenoscores (IPS) for LUAD were acquired from the Cancer Immunome Atlas (TCIA) database (http://tcia.at/home)30. The Cancer Drug Sensitivity Genomics of Cancer Cell Lines (GDSC) database (https://www.ancerrxgene.org/) were applied for assessment of potential clinical application of...
Characterization of the colon cancer immunome and its autoantibody signature from differentially-reactive antigens(DIRAGs)could provide insights into aberrant cellular mechanisms or enriched networks associated with diseases.The purpose of this study was to characterize the antibody pro?le of plasma ...