Breast Pathology: Poster#048 IMPACT OF THE NOTTINGHAM PROGNOSTIC INDEX (NPI) ON THE OCCURRENCE OF RELAPSES COMPARED WITH THE HER-2/NEU EXPRESSION IN BREAST CANCER PATIENTS.doi:10.1097/01.PAT.0000454295.14782.1fJasar, Dzengis N.Kubelka-Sabit, Katerina B....
The NGS has shown to be of independent significance with regard to breast cancer prognosis [5,7,10,11,12]. In addition, histologic grade has been incorporated in prognostic index scores, of which the Nottingham prognostic index (NPI) [13] is regarded as the only index score that has been ...
Clinicopathological parameters such as tumor size and lymph node (LN) status have been used as traditional prognostic factors and several prognostic models (e.g., Nottingham Prognostic Index [NPI]7,8, SNAP9 and PREDICT10,11) are now available to estimate the survival of breast cancer patients....
2 When administered in animal models, GSIs have a range of biological activities, including an ability to reduce the accumulation of amyloid peptides associated with Alzheimer's disease, and can induce apoptosis in a variety of tumors, included breast cancer cells.3 In this report, we focus on...
Nottingham Grading System NPI: Nottingham Prognostic Index NST: no special type RFS: relapse-free survival TNM: tumor, node, metastasis UK RCPath: Royal College of Pathologists WHO: World Health Organization.References Elston CW, Ellis IO: Pathological prognostic factors in breast cancer I...
A. et al. Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model. Cancer Lett. 299, 95–110 (2010). 18. Bum-Erdene, K. et al. Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors. Chembiochem. 14, 1331–...
Knockdown of PTBP1 prevented SASP induction in response to doxorubicin in IMR90 cells (Figures 3G and S3C), irradiation in human fibroblasts (Figure S3D), and oncogenic HER2 expression in MCF7 breast cancer cells (Figure S3E), without reverting the growth arrest (Figures 3G, S3D, and S3E)....
Bias in clinical practice, in particular in relation to race and gender, is a persistent cause of healthcare disparities. We investigated the potential of a peer-network approach to reduce bias in medical treatment decisions within an experimental settin
This is a phenotype that has only been reported in breast cancer cells39,40. Hence, it might be important to expand further studies to better understand the origin and importance of this link. Recent research has shown that embryonic stem cells and cancer stem cells not only share common ...
Similarly, a recent study by Pavlova et al [49] showed that Nectin-4 expression in breast cancer cells promotes anchorage independent cell survival and proliferation through cell-cell adhesion. Furthermore, it was found that NIH:OVCAR5 cells expressing Nectin-4 were able to migrate faster than ...