Blood Glucose Self-MonitoringDiagnostic Tests, RoutineTreatment OutcomeTime FactorsCost-Benefit AnalysisPoint-of-Care SystemsThe present invention relates to a nucleic acid molecule, a genetic construct, siRNA molecules and a composition which comprises the nucleic acid molecule and/or the genetic ...
Molecular docking is a computational technique that predicts the binding affinity of ligands to receptor proteins. Although it has potential uses in nutraceutical research, it has developed into a formidable tool for drug development. Bioactive substance
Extracellular vesicles (EVs) are small vesicles released by cells that contain biologically active molecules such as proteins and miRNAs [123]. In 2013, the Nobel Prize in Physiology or Medicine was awarded to American scientists James E. Rothman and Randy W. Schekman and German-American scientist...
The tumor microenvironment is highly dynamic, consisting of numerous cell types, including cancer cells, stem cells, immune cells such as neutrophils, macrophages, DCs, MDSCs, T-cells, B-cells, fibroblasts, adipocytes, endothelial cells, pericytes, neurons, and neuro-endocrine cells. These cells ...
Tannins are polyphenols which have the ability to precipitate protein. These compounds have been used for decades to convert raw animal hides into leather. In this process, tannin molecules crosslink the protein and make it more resistant to bacterial and fungal attack. Today, however, many substa...
In healthy nonruminant mammals, lymphocytes are the second most numerous blood leukocyte. According to conventional wisdom, cattle normally have higher numbers of lymphocytes than neutrophils in circulation. However, recent studies suggest that is no longer the case, most likely due to changes in gene...
as well as a basolateral membrane in close proximity to blood vessels and neurons that innervate the intestinal mucosa and come in close contact with the epithelial layer82. EECs contain peptides (also sometimes termed hormones) in secretory granules, and upon chemical, mechanical, or neural stimul...
contain the nucleic acid molecules or siRNA molecules according to the invention. Such a polymer can then be used as a matrix for the targeted release of the siRNA molecules, which then inhibit expression of the corresponding adhesion molecules. In this context they can be called “gene-...
The identification of components associated with “blood homeostasis”, especially hemoglobin (HBA1, HBBA), indeed suggests the presence of blood derived-molecules in PL. At last, the identification of VLDLR/LR8 receptor strongly supports that parts of the oocyte plasma membrane remained attached to...
(Fig.3c). A possible reason for the above homologous genes of the two different animals might be that theC. gigasis one of the few molluscans whose genomes have been completely sequenced and the details of numerous genes ofC. gigashave been released. The strong similarity revealed in our ...