1963 . The biosynthesis of squalene from mevalonic acid-a-C 14 and farnesyl pyrophosphate-4,8,12-C 14 by carrot and tomato enzymes . Arch. Biochem. Biophys. 102 : 26 .Beeler , D. A. , Anderson , D. G. , and Porter , J. W. , 1963, The biosynthesis of squalene from mevalonic ...
Gliocladium deliquescensbiosynthesissteroidviridiolThe incorporation of squalene, lanosterol, dehydroxydemethoxyviridin and demethoxyviridin into viridiol by the fungus, Gliocladium deliquescens, is described.doi:10.1016/0031-9422(88)83104-2Elsevier LtdPhytochemistry...
Define squalene. squalene synonyms, squalene pronunciation, squalene translation, English dictionary definition of squalene. n. An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as chole
The biosynthesis of the triterpenoid alcohol tetrahymanol by Tetrahymena pyriformis is rapidly inhibited by the addition of cholesterol to the growth medium. The primary site of this inhibition by cholesterol has been established to be at the level of the enzyme squalene synthetase. The protein ...
The isoprenoid squalene is an important precursor for the biosynthesis of sterols. The cellular storage of squalene and its impact on membrane properties have been the subject of recent investigations. In a screen for abnormal lipid droplet morphology and distribution in the yeast Saccharomyces cerevisia...
Influence of vitamin a deficiency on the biosynthesis of cholesterol, squalene and ubiquinone Racemic mevalonic acid labelled with 14C was injected intraperitoneally into rats depleted of vitamin A (see Gloor and Wiss, Arch. Biochem. Biophys. 1959, ... U Gloor,O Wiss - 《Biochemical & Biophysical...
The flavonoid xanthohumol is an important flavor substance in the brewing industry that has a wide variety of bioactivities. However, its unstable structure results in its low content in beer. Microbial biosynthesis is considered a sustainable and econom
The biosynthesis of terpenoids is reported to be regulated by a variety of transcription factors. For example, MYB and MYC were found to work cooperatively in controlling the expression of terpene synthase genes. In the myb21 mutant of Arabidopsis, it was observed that the emission of sesquiterpen...
Cholesterol is the major component of lipid rafts. Squalene synthase (SQS) is a cholesterol biosynthase that functions in cholesterol biosynthesis, modulates the formation of lipids rafts and promotes lung cancer metastasis. In this study, we investigate
Florova G, Lindsay YM, Brown MS, McArthur HAI, Denoya CD, Reynolds KA (1998) Stereochemical analyses of the Streptomyces hygroscopicus var. ascomyceticus type-II dehydroquinate dehydratase and evidence for a role of the enzyme in the biosynthesis of the shikimate-derived moiety of ascomycin. ...