biology metabolism nucleic acid pharmacology protein toxicology Search within this book Search Table of contents (12 chapters) Front Matter Pages i-xix Download chapter PDF Delivery Routes to the Lysosome The Taxonomy of Lysosomes and Related Structures John B. Lloyd Pages 1-13 Origin of ...
Is streptolysin S of group A streptococci a virulence factor? APMIS 107, 1051–1059 (1999). Article CAS PubMed Google Scholar Keiser, H., Weissmann, G. & Bernheimer, A. W. Studies on lysosomes. IV. Solubilization of enzymes during mitochondrial swelling and disruption of lysosomes by ...
Studies of the cell biology of extracellular vesicles is not only essential for addressing cell biological questions but also critical to open new avenues for their clinical use as biomarkers, as cargo vehicles for the targeted delivery of compounds or as specific modulators of cell behaviours. Abstr...
Andrews, N. W. Regulated secretion of conventional lysosomes.Trends Cell Biol.10, 316–321 (2000). CASPubMedGoogle Scholar Reddy, A., Caler, E. V. & Andrews, N. W. Plasma membrane repair is mediated by Ca2+-regulated exocytosis of lysosomes.Cell106, 157–169 (2001). CASPubMedGoogle ...
MVBs can be either fused with lysosomes or with the plasma membrane, which allows the release of their contents to the extracellular milieu. RAB and SNARE are involved in the transport of MVBs to the plasma membrane and secretion of exosomes. 1.2.1. The mechanism of exosome biogenesis The ...
Alberts Molecular Biology Of The Cell 资源描述: the molecular biology of the cell acknowledgments preface a note to the reader i introduction to the cell 1 cells and genomes the universal features of cells on earth the diversity of genomes and the tree of life genetic information in eucaryotes...
Here, through an unknown mechanism, uptake and degradation of Borrelia in lysosomes introduces PGN to the cytosol and stimulates NOD2/RIPK2-mediated NF-κB activation and inflammatory cytokine production [167]. 2.1.1. RIPK2 and autophagy as a host response to bacterial infection RIPK2 induces ...
Lymphocytes and the Cellular Basis of Adaptive Immunity B Cells and Antibodies The Generation of Antibody Diversity T Cells and MHC Proteins Helper T Cells and Lymphocyte Activation References 25. Pathogens, Infection, and Innate Immunity Introduction to Pathogens Cell Biology of Infection Innate Immunity...
These bind both ubiquitin and microtubule-associated protein light chain 3 (LC3), promoting the sequestration of ppUb-labelled mitochondria within autophagosomes to be degraded later after fusion with lysosomes. The relationship between PINK1 and Parkin, and the phospho-polyubiqutin chains that the ...
Ablation of FRMD8 triggers the mis-sorting of iRhom2 and ADAM17 to lysosomes, where they are degraded [53]. Consistent with this, loss of FRMD8 results in a dramatic reduction in ADAM17 activity and tumor necrosis factor (TNF) secretion, revealing FRMD8 as a key physiological regulator ...